Results 81 to 90 of about 1,290,135 (272)

Paralytic Shellfish Toxins (PST)-Transforming Enzymes: A Review

open access: yes, 2020
Paralytic shellfish toxins (PSTs) are a group of toxins that cause paralytic shellfish poisoning through blockage of voltage-gated sodium channels.
Maria João Botelho   +3 more
core   +1 more source

Multifunctional Manganese Oxide Nanocomposite Hydrogel With Synergistic Reactive Oxygen Species‐Scavenging, Oxygen‐Generating, Immunomodulatory, and Photothermal Antimicrobial Activities for Enhanced Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
CFP/PC@MnO2 hydrogel integrates ROS scavenging, oxygen delivery, oxidative stress reduction, immunomodulation, and photothermal antibacterial properties. The incorporation of PC@MnO2 NPs endows the hydrogel with multiple functional advantages tailored to the pathological microenvironment of diabetic wounds, including efficient ROS clearance, mitigation
Zhi Xu   +9 more
wiley   +1 more source

Noncanonical Peloruside A Biosynthesis by an Uncultivated Verrucomicrobiota Symbiont

open access: yesAngewandte Chemie, EarlyView.
Noncanonical biochemistry of the peloruside PKS characterized in this work, comprising double bond generation by a noncanonical tridomain (blue), acetyl‐CoA recycling (orange), and proofreading systems (purple and yellow). The Z‐double bond is installed by TEB1 through O‐acetylation and acetate elimination. The acyl ligase PelB (AL, orange) selectively
Amy E. Fraley   +11 more
wiley   +2 more sources

Neurotoxic Syndromes in Marine Poisonings a Review

open access: yesIranian South Medical Journal, 2014
Background: Marine neurotoxins as of Marine biotoxins are natural toxins that produced mainly by dinoflagellates, diatoms and several species of invertebrates and fish.
Gholam Hossein Mohebbi   +2 more
doaj  

Exploration of Toxins from a Marine Annelid: An Analysis of Phyllotoxins and Accompanying Bioactives

open access: yesAnimals
Proteinaceous toxins are peptides or proteins that hold great biotechnological value, evidenced by their ecological role, whether as defense or predation mechanisms.
Ana P. Rodrigo   +3 more
doaj   +1 more source

No evidence for a culturable bacterial tetrodotoxin producer in Pleurobranchaea maculata (Gastropoda: Pleurobranchidae) and Stylochoplana sp. (Platyhelminthes: Polycladida) [PDF]

open access: yes, 2015
Tetrodotoxin (TTX) is a potent neurotoxin found in the tissues of many taxonomically diverse organisms. Its origin has been the topic of much debate, with suggestions including endogenous production, acquisition through diet, and symbiotic bacterial ...
Salvitti, Lauren R.   +10 more
core   +1 more source

Comparison of Strategies to Overcome Drug Resistance: Learning from Various Kingdoms

open access: yesMolecules, 2018
Drug resistance, especially antibiotic resistance, is a growing threat to human health. To overcome this problem, it is significant to know precisely the mechanisms of drug resistance and/or self-resistance in various kingdoms, from bacteria through ...
Hiroshi Ogawara
doaj   +1 more source

OMICs Approaches in Diarrhetic Shellfish Toxins Research

open access: yesToxins, 2020
Diarrhetic shellfish toxins (DSTs) are among the most prevalent marine toxins in Europe’s and in other temperate coastal regions. These toxins are produced by several dinoflagellate species; however, the contamination of the marine trophic chain is often
Alexandre Campos   +7 more
doaj   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

open access: yesAdvanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries   +25 more
wiley   +1 more source

Stabilizing Zinc Anodes via a Zeolite‐Induced Localized Supersaturated Electrolyte Interface

open access: yesAngewandte Chemie, EarlyView.
A low‐Si/Al‐ratio ZSM‐5 (LZ5) interphase induces a localized supersaturated electrolyte interface on Zn, with a local Zn2+ concentration exceeding 10 M in a 1 M ZnSO4 bulk electrolyte. Continuous Zn2+ enrichment within the zeolite nanochannels creates an H2O‐deficient, anion‐enriched solvation environment, promoting rapid desolvation, uniform ...
Xiaoqi Liu   +12 more
wiley   +2 more sources

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