Results 131 to 140 of about 269,198 (309)

Molecular marker-assisted selection for seedlessness in atemoya breeding

Crop Breeding and Applied Biotechnology, 2022
Perennial plant breeding is an expensive and time-consuming process, mainly due to the extended growth time for juveniles. In these cases, the use of molecular marker-assisted selection (MMAS) allows for the selectionof a characteristic of interest at ...
Bruno Rafael Alves Rodrigues, Silvia Nietsche, Samy Pimenta, Marlon Cristian Toledo Pereira   +3 more
doaj  

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

MOLECULAR MARKERS: IMPLEMENTATION IN CROP PLANT BREEDING FOR IDENTIFICATION, INTROGRESSION, AND GENE PYRAMIDING

Вавиловский журнал генетики и селекции, 2014
Over the past decades, wide theoretical and practical experience has been obtained in application of DNA markers for investigation of plant genetic diversity, construction of molecular genetic maps, mapping of genes and quantitative trait loci, and ...
I. N. Leonova
doaj  

Genetic bases of tomatо marker-assisted selection in Belarus

The EuroBiotech Journal, 2018
To develop tomato hybrids and varieties with a high fruit quality, we gradually solved the following tasks: development of DNA-marking methods for long shelf life genes; the genes modifying the biosynthesis of carotenoids and their composition; testing ...
Babak Olga G., Nekrashevich Natalia A., Yatsevich Konstantsia K., Malyshev Sergey V., Kilchevsky Alexander V.   +4 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Genome-wide prediction of testcross performance and phenotypic stability for important agronomic and quality traits in elite hybrid rye (Secale cereale L.) [PDF]

, 2016
Genomic selection offers a greater potential for improving complex, quantitative traits in winter rye than marker-assisted selection. Prediction accuracies for grain yield for unrelated test populations have, however, to be improved.
Wang, Yu
core  

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Breeding Aromatic Rice Restorer by Specific Fragrant Molecular Marker-assisted Selection [PDF]

, 2015
水稻是最重要的粮食作物之一，香稻因其米饭清香、口感好以及市场价格高等优势而倍受人们青睐。由于传统香稻品种大多产量低、抗性弱且有地域性限制，导致其推广种植面积受到限制；而且传统的香稻育种方式耗时长、准确率低，使香稻品种的开发缓慢低效。随着分子生物技术的飞速发展，借助分子标记辅助选择开展香稻育种可以提高香味选择准确率，加快育种进程。为此，本研究应用分子标记辅助选择技术与传统育种技术相结合的方法，选用优良水稻恢复系福恢673、明恢86和闽恢3301为受体亲本，分别与香味基因供体亲本优质香稻品种象牙香占杂交 ...
高筱莎
core