Results 21 to 30 of about 2,008,767 (268)

Handling Marker-Marker Linkage Disequilibrium: Pedigree Analysis with Clustered Markers [PDF]

The American Journal of Human Genetics, 2005
Single-nucleotide polymorphisms (SNPs) are rapidly replacing microsatellites as the markers of choice for genetic linkage studies and many other studies of human pedigrees. Here, we describe an efficient approach for modeling linkage disequilibrium (LD) between markers during multipoint analysis of human pedigrees.
Abecasis, Gonçalo R., Wigginton, Janis E.   +1 more
openaire   +2 more sources

The clinical value of serum TPS in gynecological malignancies

The International Journal of Biological Markers, 1995
This study included 75 cases; 39 with gynecological cancer of different types, stages, and grades (14 ovarian, 11 endometrial, 9 cervical, and 5 vulvovaginal); 23 patients with benign gynecological diseases and 13 normal healthy controls.
T. Salman, O. El-Ahmady, M.R. Sawsan, M.H. Nahed   +3 more
doaj   +1 more source

TPS Monitoring in Metastatic Breast Cancer

The International Journal of Biological Markers, 1999
The management of metastatic breast cancer patients reflects the heterogeneous nature of the disease. While patients may benefit from hormonal treatment, in most cases more toxic chemotherapy is applied in the advanced stages.
A. Van Dalen
doaj   +1 more source

pH-Responsive DNA Motif: From Rational Design to Analytical Applications

Frontiers in Chemistry, 2021
pH-responsive DNA motifs have attracted substantial attention attributed to their high designability and versatility of DNA chemistry. Such DNA motifs typically exploit DNA secondary structures that exhibit pH response properties because of the presence ...
Lin Lin Zheng, Jin Ze Li, Ying Xu Li, Jian Bang Gao, Jiang Xue Dong, Zhong Feng Gao   +5 more
doaj   +1 more source

Reducing Exposures to Endocrine Disruptors (REED) study, a personalized at-home intervention program to reduce exposure to endocrine disrupting chemicals among a child-bearing age cohort: study protocol for a randomized controlled trial

Trials
Background Exposures to endocrine disrupting chemicals (EDCs) have been linked to chronic diseases including breast cancer, metabolic syndrome, diabetes, and infertility. Exposure during pregnancy may have a lifelong impact on the fetus.
Johanna R. Rochester, Carol F. Kwiatkowski, Michael Kupec Lathrop, Iva Neveux, Eric J. Daza, Joseph Grzymski, Jenna Hua   +6 more
doaj   +1 more source

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij, Catia Olianti, Herve Brisse, Pier Luigi Di Paolo, Maria Garganese, Tejas Kapadia, Jurgen Schaefer, Hugh Wallace, Simon Wan, Bart de Keizer, Irmina Sefic Pasic, Julian Rogasch   +11 more
wiley   +1 more source

Marker-of-self becomes marker-of-senescence [PDF]

Blood, 2012
In this issue of Blood , Burger et al provide compelling in vitro evidence that phagocytic uptake of aged human erythrocytes is promoted by the marker of self CD47 in complex with the serum factor thrombospondin-1.[1][1] CD47 is expressed on cells of all types and binds and signals to SIRPα ...
Nisha, Sosale, Dennis E, Discher
openaire   +2 more sources

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

A Facile Method for Screening DPP IV Inhibitors in Living Cell System Based on Enzyme Activity Probe

Journal of Analytical Methods in Chemistry
Dipeptidyl peptidase IV (DPP IV), one of the most essential peptidase, is widely distributed in various organs and tissues of the human body, which affects protein stability by acting on peptide bonds at the end of peptide chains and is further involved ...
Shu-Mei Pan, Chun-Yu Xing, Hong-Wei Li, Rui-Min Wang, Xin-Yue Pu, Tie-Gang Wang, Dan-Dan Wang, Li-Wei Zou   +7 more
doaj   +1 more source

Horowski, Das Europa der Könige (Rowohlt, 2018)

Royal Studies Journal, 2020
Review of Leonhard Horowski, Das Europa der Könige (Hamburg: Rowohlt, 2018).
Juliane Märker
doaj   +1 more source