Results 141 to 150 of about 270,162 (309)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Molecular Marker-Assisted Selection for Frost Tolerance in a Diallel Population of Potato. [PDF]

Cells, 2023
Tu W, Li J, Dong J, Wu J, Wang H, Zuo Y, Cai X, Song B.   +7 more
europepmc   +1 more source

Analysis of nucleotide diversity in Coffea spp. (W153) [PDF]

, 2011
Marker-assisted selection becomes a reality for many crops; in perennial crops, the utilization of molecular markers in breeding programs can speed up genotype selection. However, the most important commercial coffee species - allotetraploid C. arabica -
Domingues, Douglas S., Ferreira, Lucia Pires, Pereira, Luiz Filipe P., Pot, David, Vieira, Luiz Gonzaga Esteves, Yanagui, Karina   +5 more
core  

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

A simulation study comparing advanced marker-assisted selection with genomic selection in tree breeding programs. [PDF]

G3 (Bethesda), 2023
Degen B, Müller NA.
europepmc   +1 more source

Rice and Water: The Final Frontier [PDF]

, 2004
Outlines the threat of diminishing water resources for rice crops, the economic and social dimensions of the droughts' potential effects, and the new cultural systems and adapted rice varieties being pursued as potential ...
John C. O'Toole
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Identification and Validation of Quantitative Trait Loci Associated with Fruit Puffiness in a Processing Tomato Population

Plants
Physiological disorders impact the yield and quality of marketable fruit in tomato. Puffy fruit caused by cavities inside the locule can be problematic for processing and fresh market quality.
Françoise Dalprá Dariva, Su Subode, Jihuen Cho, Carlos Nick, David Francis   +4 more
doaj   +1 more source

Marker-assisted selection for transfer of QTLs to a promising line for drought tolerance in wheat (Triticum aestivum L.). [PDF]

Front Plant Sci, 2023
Sunilkumar VP, Krishna H, Devate NB, Manjunath KK, Chauhan D, Singh S, Sinha N, Singh JB, T L P, Pal D, Sivasamy M, Jain N, Singh GP, Singh PK.   +13 more
europepmc   +1 more source