Results 41 to 50 of about 3,588,030 (299)

High resolution mapping of a novel late blight resistance gene Rpi-avll, from the wild Bolivian species Solanum avilesii [PDF]

, 2011
Both Mexico and South America are rich in Solanum species that might be valuable sources of resistance (R) genes to late blight (Phytophthora infestans). Here, we focus on an R gene present in the diploid Bolivian species S. avilesii.
Visser, R.G.F., Vossen, E.A.G., van der, Vleeshouwers, V.G.A.A., Niks, R.E., Vetten, N., de, Verzaux, E.C., Jacobsen, E., Budding, D.J.   +7 more
core   +1 more source

A method to optimize selection on multiple identified quantitative trait loci

Genetics Selection Evolution, 2002
A mathematical approach was developed to model and optimize selection on multiple known quantitative trait loci (QTL) and polygenic estimated breeding values in order to maximize a weighted sum of responses to selection over multiple generations.
Dekkers Jack CM, Moreau Laurence, Chakraborty Reena   +2 more
doaj   +1 more source

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho, Emmanuella Amoako, Nihad Salifu, Lily Gloria Tagoe, Yaw Bediako, Michelle Hermiston, Catherine Segbefia   +6 more
wiley   +1 more source

Response to mass selection when an identified major gene is segregating [PDF]

, 1998
A deterministic model to predict response with mass selection when a major locus is segregating is presented. The model uses a selection index framework in which the weight of the different components included in the index are adjusted to describe the ...
Ricardo Pong-Wong, Pong-Wong, R.; id_orcid, John A. Woolliams, Woolliams, John, John A Woolliams   +4 more
core   +1 more source

Optimizing purebred selection for crossbred performance using QTL with different degrees of dominance

Genetics Selection Evolution, 2004
A method was developed to optimize simultaneous selection for a quantitative trait with a known QTL within a male and a female line to maximize crossbred performance from a two-way cross. Strategies to maximize cumulative discounted response in crossbred
Chakraborty Reena, Dekkers Jack CM
doaj   +1 more source

Marker-Assisted Pyramiding of Genes for Multilocular Ovaries, Self-Compatibility, and Clubroot Resistance in Chinese Cabbage (Brassica rapa L. ssp. pekinensis)

Horticulturae, 2022
Molecular marker-assisted gene pyramiding combined with backcrossing has been widely applied for crop variety improvement. Molecular marker identification could be used in the early stage of breeding to achieve the rapid and effective pyramiding of ...
Jingyi Zheng, Huicai Zhao, Yingmei Ma, Mingliang Jiang, Zongxiang Zhan, Xiaonan Li, Zhongyun Piao   +6 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Potential benefit from using an identified major gene in BLUP evaluation with truncation and optimal selection [PDF]

, 1999
This study investigates the benefit of including information on an identified major gene in the estimation of breeding values in BLUP selection programmes. Selection for a quantitative trait is controlled by polygenes and a major locus with known effect.
Ricardo Pong-Wong, Grundy, B, Woolliams, JA, Villanueva, B., Pong-Wong, R.; id_orcid, Beatriz Villanueva, Villanueva, B, Pong-Wong, R, John A. Woolliams, Grundy, B., Woolliams, John, Brian Grundy   +11 more
core   +1 more source

R-ISSR As Marker Assisted Selection For Drought Tolerance In Sugarcane [PDF]

Journal of Agricultural Chemistry and Biotechnology, 2017
Sugarcane is one of the most important crops in the world for its syrup and by-products. Eight sugarcane genotypes (i.e.G.T.54-9, G84-47, Sp 80-32-80, F.153, Co.997, BOT-41, Co.775, and F.161) were kindly provided by Sugar Crops Research Institute (SCRI),
A. Abdelhadi, Sheren El sherbeny, K. Khaled   +2 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source