Results 11 to 20 of about 6,228,391 (354)
Over the last decade, the immune checkpoint blockade targeting the programmed death protein 1 (PD-1)/programmed death ligand 1 (PD-L1) axis has improved progression-free and overall survival of advanced non-small cell lung cancer (NSCLC) patients.
Vera Kloten +3 more
doaj +1 more source
Alzheimer’s disease (AD) is a pathology characterized by the accumulation in the brain of intracellular and extracellular amyloid-β (Aβ) aggregates, especially of Aβ1–40 and Aβ1–42 peptides.
Guido Domingo +11 more
doaj +1 more source
In 1899, French poet Alcanter de Brahm proposed that ironists should use a specific punctuation mark known as the ironic sign to guide their readers explicitly in an ironic interpretation of an utterance. The irony mark would be a spoiler alert, and thereby reduce the pleasure of using irony. In order to help the receiver to detect the intention of the
Burgers, C., van Mulken, M.
openaire +4 more sources
Inference of population structure using multilocus genotype data: dominant markers and null alleles
Dominant markers such as amplified fragment length polymorphisms (AFLPs) provide an economical way of surveying variation at many loci. However, the uncertainty about the underlying genotypes presents a problem for statistical analysis.
D. Falush, M. Stephens, J. Pritchard
semanticscholar +1 more source
Molecular Pathways Bridging Frontotemporal Lobar Degeneration and Psychiatric Disorders
The overlap of symptoms between neurodegenerative and psychiatric diseases has been reported. Neuropsychiatric alterations are commonly observed in dementia, especially in the behavioral variant of frontotemporal dementia (bvFTD), which is the most ...
Roberta eZanardini +3 more
doaj +1 more source
Variable number of tandem repeat markers in the genome sequence of Mycosphaerella fijiensis, the causal agent of black leaf streak disease of banana (Musa spp) [PDF]
. We searched the genome of Mycosphaerella fijiensis for molecular markers that would allow population genetics analysis of this plant pathogen. M. fijiensis, the causal agent of banana leaf streak disease, also known as black Sigatoka, is the most ...
Ferreira, C.F. +8 more
core +4 more sources
MDSC: Markers, development, states, and unaddressed complexity.
Myeloid-derived suppressor cells (MDSCs) are one of the most discussed biological entities in immunology. While the context and classification of this group of cells has evolved, MDSCs most commonly describe cells arising during chronic inflammation ...
Samarth Hegde, A. Leader, M. Merad
semanticscholar +1 more source
Alzheimer’s disease (AD), dementia with Lewy bodies (DLB) and frontotemporal dementia (FTD) represent the three major neurodegenerative dementias characterized by abnormal brain protein accumulation. In this study, we investigated extracellular vesicles (
Antonio Longobardi +12 more
doaj +1 more source
A new and versatile method for the successful conversion of AFLP-TM markers into simple single locus markers [PDF]
Genetic markers can efficiently be obtained by using amplified fragment length polymorphism (AFLP) fingerprinting because no prior information on DNA sequence is required.
Brugmans, B.W. +4 more
core +2 more sources
Imaging Markers in Genetic Forms of Parkinson’s Disease
Parkinson’s disease (PD) is a complex neurodegenerative disorder characterized by motor symptoms such as bradykinesia, rigidity, and resting tremor.
Amgad Droby, Avner Thaler, Anat Mirelman
doaj +1 more source

