Results 61 to 70 of about 112,632 (333)

Bayesian clustering of multivariate extremes

open access: yesCanadian Journal of Statistics, EarlyView.
Abstract The asymptotic dependence structure between multivariate extreme values is fully characterized by their projections on the unit simplex. Under mild conditions, the only constraint on the resulting distributions is that their marginal means must be equal, which results in a nonparametric model that can be difficult to use in applications ...
Sonia Alouini, Anthony C. Davison
wiley   +1 more source

Distance between configurations in Markov chain Monte Carlo simulations

open access: yesJournal of High Energy Physics, 2017
For a given Markov chain Monte Carlo algorithm we introduce a distance between two configurations that quantifies the difficulty of transition from one configuration to the other configuration.
Masafumi Fukuma   +2 more
doaj   +1 more source

When Dihedral Angles Mask Denticity in Molecular Conductance

open access: yesChemPhysChem, EarlyView.
This study tests whether higher molecule–electrode denticity increases conductance in single‐molecule junctions. Using nonequilibrium Green's function technique in conjunction with density functional theory simulations and mechanically controlled break‐junction experiments on a tetradentate N‐heterohexacene, it is found that conductance depends mainly ...
Kevin Batzinger   +8 more
wiley   +1 more source

Population Pharmacokinetics and Exposure–Response Analyses of Momelotinib, Its Active Metabolite (M21), and Total Active Moiety in Myelofibrosis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Momelotinib, a Janus kinase (JAK) 1/JAK2/activin A receptor type 1 inhibitor, is approved for the treatment of myelofibrosis with anemia. These analyses characterized the population pharmacokinetics of momelotinib and its active metabolite M21 following administration of the commercial tablet formulation in patients with myelofibrosis from phase II/III
Benjamin Rich   +5 more
wiley   +1 more source

MCMCpack: Markov Chain Monte Carlo in R

open access: yesJournal of Statistical Software, 2011
We introduce MCMCpack, an R package that contains functions to perform Bayesian inference using posterior simulation for a number of statistical models. In addition to code that can be used to fit commonly used models, MCMCpack also contains some useful ...
Andrew D. Martin   +2 more
doaj  

Straight to Phase III: Model‐Informed Approach Speeds Depemokimab Clinical Development in Interleukin‐5‐Driven Diseases

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Straight to Phase III: Model‐informed approach speeds depemokimab clinical development in interleukin‐5‐driven diseases. IL‐5, a key mediator of type 2 inflammation, underlies various diseases, including severe asthma, CRSwNP, EGPA, and HES. Reduction in blood eosinophil count (BEC), a biomarker of IL‐5 activity, is commonly used to evaluate the ...
Chiara Zecchin   +6 more
wiley   +1 more source

Hybrid Censoring Schemes with Mixture Gamma Failure Distribution

open access: yesJournal of Mathematics, 2021
Censoring schemes have received much attention over the past decades. Hybrid censoring schemes are censoring schemes mixed of type-I (T-1) and type-II (T-2) censoring schemes, a most popular area of study in life-testing or reliability experiments.
Hassan M. Aljohani, Nada M. Alfaer
doaj   +1 more source

Patterns of understorey bird diversity across Amazonian forests: survey effort and range maps predict local species richness

open access: yesEcography, EarlyView.
Species diversity typically increases from higher to lower latitudes, but the regional‐scale variation along this geographic gradient remains unclear. It has been suggested that species diversity throughout Amazonia generally increases westward toward the Andes, but this pattern and its environmental determinants require further investigation for most ...
Pilar L. Maia‐ Braga   +14 more
wiley   +1 more source

Markov Chain Monte Carlo

open access: yes, 2020
As we have seen, in the previous chapter, in a Markov chain we have the following two types of distributions, leading to a joint distribution.
Nicolas Chopin, Omiros Papaspiliopoulos
openaire   +2 more sources

Sample caching Markov chain Monte Carlo approach to boson sampling simulation

open access: yesNew Journal of Physics, 2020
Boson sampling is a promising candidate for quantum supremacy. It requires to sample from a complicated distribution, and is trusted to be intractable on classical computers.
Yong Liu   +12 more
doaj   +1 more source

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