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Modelling in economic evaluations of medicines [PDF]
Economic evaluation in health (also known as pharmacoeconomic in case of medicines) identifies, measures, and values costs and outcomes of alternative healthcare technologies, and can be performed alongside controlled clinical trials, but analytical ...
Lakić Dragana+3 more
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Markov model- Quantifying outlook towards success of tobacco cessation counseling
Smoking is still a major public health issue that causes morbidity and mortality all over the world. The percentage of deaths caused by tobacco smoking has escalated from 1.4% in 1990 to 13.3% by 2020.
Yashasvi Nikose+6 more
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Assessment of the protection level of continuous production based on the Markov life cycle model [PDF]
The article discusses the current level of development of automation technologies for continuous production, taking into account the compliance with the requirements of the fourth industrial revolution Industry 4.0.
Petrov, Dmitry Yurievich
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Finite state machine and Markovian equivalents of the lac Operon in E. coli bacterium
The lac operon in E. coli has been extensively studied by computational biologists. The bacterium uses it to survive in the absence of glucose, utilizing lactose for growth.
Urooj Ainuddin, Maria Waqas
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Discrete Time Hybrid Semi-Markov Models in Manpower Planning
Discrete time Markov models are used in a wide variety of social sciences. However, these models possess the memoryless property, which makes them less suitable for certain applications.
Brecht Verbeken, Marie-Anne Guerry
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Gene hunting with hidden Markov model knockoffs [PDF]
&NA; Modern scientific studies often require the identification of a subset of explanatory variables. Several statistical methods have been developed to automate this task, and the framework of knockoffs has been proposed as a general solution for ...
Matteo Sesia, C. Sabatti, E. Candès
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Objective: The ORIENT-32 clinical trial revealed that sintilimab plus bevacizumab biosimilar significantly improved the median progression-free survival and median overall survival (OS) compared with sorafenib.
Ye Peng+10 more
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Using Multi-state Markov models to predict the probability of borrowers’ default [PDF]
Introduction. After the crises, lenders realized the importance of assessing the risk of default on loan portfolios in various economic conditions. Modeling of credit risk assessment occurs mainly using internal ratings of banks based on probabilistic ...
Balash, Vladimir A.+2 more
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Concentration of inverted repeats along human DNA
This work aims to describe the observed enrichment of inverted repeats in the human genome; and to identify and describe, with detailed length profiles, the regions with significant and relevant enriched occurrence of inverted repeats.
Bastos Carlos A. C.+3 more
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Hierarchical Model Predictive Control for Hydraulic Hybrid Powertrain of a Construction Vehicle
Hybrid hydraulic technology has the advantages of high-power density and low price and shows good adaptability in construction machinery. A complex hybrid powertrain architecture requires optimization and management of power demand distribution and an ...
Zhong Wang, Xiaohong Jiao
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