Results 61 to 70 of about 660,114 (325)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Nambu monopoles interacting with lattice defects in two-dimensional artificial square spin ice

, 2013
The interactions between an excitation (similar to a pair of Nambu monopoles) and a lattice defect are studied in an artificial two-dimensional square spin ice.
A. R. Pereira, G. M. Wysin, H. Zabel, L. A. S. Mól, R. C. Silva, R. J. C. Lopes, W. A. Moura-Melo   +6 more
core   +1 more source

Nuclear resonant surface diffraction [PDF]

, 2017
Nuclear resonant x-ray diffraction in grazing incidence geometry is used to determine the lateral magnetic configuration in a one-dimensional lattice of ferromagnetic nanostripes.
Bocklage, Lars, Dzemiantsova, Liudmila, Meier, Guido, Pues, Matthias, Röhlsberger, Ralf, Schlage, Kai, Wille, Hans-Christian   +6 more
core   +1 more source

Discrete Hall resistivity contribution from Néel skyrmions in multilayer nanodiscs [PDF]

Nature Nanotechnology, 2017
Magnetic skyrmions are knot-like quasiparticles. They are candidates for non-volatile data storage in which information is moved between fixed read and write terminals.
K. Zeissler, S. Finizio, Kowsar Shahbazi, J. Massey, F. A. Ma’Mari, D. Bracher, A. Kleibert, M. Rosamond, E. Linfield, T. Moore, J. Raabe, G. Burnell, C. Marrows   +12 more
semanticscholar   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Time dependence studies on giant magnetoresistive Co/Cu multilayers [PDF]

, 2000
Time dependence studies consisting of applying current steps at fixed applied fields have been carried out on bilinear and biquadratic giant magnetoresistive (GMR) Co/Cu multilayers in a temperature controlled environment.
Hickey, B.J., Hill, E.W., Holliday, N.T., Marrows, C.H., Stanley, F.E.   +4 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Myelodysplasia in autosomal dominant and sporadic monocytopenia immunodeficiency syndrome: diagnostic features and clinical implications

Haematologica, 2011
A novel, genetic immunodeficiency syndrome has been recently described, herein termed “MonoMAC”. It is characterized by severe circulating monocytopenia, NK- and B-lymphocytopenia, severe infections with M. avium complex (MAC), and risk of progression to
Katherine R. Calvo, Donald C. Vinh, Irina Maric, Weixin Wang, Pierre Noel, Maryalice Stetler-Stevenson, Diane C. Arthur, Mark Raffeld, Amalia Dutra, Evgenia Pak, Kyungjae Myung, Amy P. Hsu, Dennis D. Hickstein, Stefania Pittaluga, Steven M. Holland   +14 more
doaj   +1 more source

Diffusive and ballistic current spin-polarization in magnetron-sputtered L1o-ordered epitaxial FePt

, 2007
We report on the structural, magnetic, and electron transport properties of a L1o-ordered epitaxial iron-platinum alloy layer fabricated by magnetron-sputtering on a MgO(001) substrate.
A. B. Pippard, A. D. Kent, A. F. Andreev, B. E. Warren, B. Raquet, Bryan J. Hickey, Christopher H. Marrows, H. A. M. van den Berg, I. A. Campbell, J. W. F. Dorleijn, John N. Chapman, Klaus M. Seemann, Maureen MacKenzie, R. C. O’Handley, S. Chikazumi, Vincent Baltz   +15 more
core   +3 more sources