Results 81 to 90 of about 14,366 (278)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Degeneracy and criticality from emergent frustration in artificial spin ice

, 2013
Although initially introduced to mimic the spin-ice pyrochlores, no artificial spin ice has yet exhibited the expected degenerate ice-phase with critical correlations similar to the celebrated Coulomb phase in the pyrochlore lattice.
Chern, Gia-Wei, Morrison, Muir J., Nisoli, Cristiano   +2 more
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Somatic mutations in STAG2 are associated with separated megakaryocyte nuclear lobes in myelodysplastic syndromes

Blood Advances
: Myelodysplastic syndrome (MDS) is driven by genetic mutations, but diagnosis relies on morphologic evaluation of bone marrow hematopoiesis. Only a small number of genetic abnormalities define specific bone marrow morphologic features in MDS, such as ...
Waihay J. Wong, Rebecca L. Zon, Christopher J. Gibson, Caleb Ho, Olga Pozdnyakova, Donna Neuberg, Elisabeth M. Battinelli, Marlise R. Luskin, Zuzana Tothova, Elizabeth A. Morgan, Benjamin L. Ebert   +10 more
doaj   +1 more source

Karyotype of Hairless Guinea pig [PDF]

Journal of Sciences, Islamic Republic of Iran, 2013
Chromosomal patterns of experimental animals are useful tools for cytogenetics research and animal breeding. Chromosome investigations of the hairless guinea pig are rare, therefore, karyotype of hairless guinea pigs (twelve male and female) was studied ...
fatemeh Todehdehghani, Mohammah hassan motedayen, Shohreh Teimorzadeh   +2 more
doaj  

Long-ranged magnetic proximity effects in noble metal-doped cobalt probed with spin-dependent tunnelling

New Journal of Physics, 2014
We inserted non-magnetic layers of Au and Cu into sputtered AlO $_{x}$ -based magnetic tunnel junctions and Meservey–Tedrow junctions in order to study their effect on tunnelling magnetoresistance (TMR) and spin polarization (TSP).
M S Gabureac, D A MacLaren, H Courtois, C H Marrows   +3 more
doaj   +1 more source

Bone marrow cytological evaluation in dogs with chronic kidney disease

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2014
Since anemia is indicated as an important compromising factor for the quality of life of dogs with chronic kidney disease (CKD), bone marrow cytological analysis may provide more information on the hematological profile ...
S. Borin-Crivellenti, L.Z. Crivellenti, M.B. Carvalho, A.E. Santana   +3 more
doaj   +1 more source

Comment: Superconducting transition in Nb nanowires fabricated using focused ion beam [PDF]

, 2010
In a recent paper Tettamanzi et al (2009 Nanotechnology \bf{20} 465302) describe the fabrication of superconducting Nb nanowires using a focused ion beam.
A Engel, Bezryadin A, Il’in K S Siegel M Semenov A D Engel A Hübers H-W Andreone A Pepe G P Cristiano R Masullo G, Tettamanzi G C   +3 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Clinico-hematological profile of dimorphic anemia

Journal of Applied Hematology, 2017
Dimorphic anemia (DA) is characterized by two different cell populations. One population is of microcytic hypochromic and other being either normocytic or macrocytic. A retrospective study was undertaken to correlate and compare the clinico-hematological
Pooja Garg, Biswajit Dey, Archana Hemant Deshpande, Jyotsna Naresh Bharti, Jitendra Singh Nigam   +4 more
doaj   +1 more source