Results 151 to 160 of about 994,793 (297)

THE SATELLITES OF MARS [PDF]

Science, 1908
openaire   +2 more sources

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

FEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti, Bruna Lopes Correia, Francielle Cristina Nakamura Manicardi, Nairana Mithieli de Queiroz Eskuarek Melo, Vanesa de Oliveira Pateis, Jurandir Fernando Comar, Anacharis Babeto de Sá‐Nakanishi, Adelar Bracht, Lívia Bracht   +8 more
wiley   +1 more source

The Politics of Addiction: Medical Conflict and Drug Dependence in England since the 1960s [PDF]

, 2012
Mars, SG
core   +2 more sources

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Mars transfer vehicle studies [PDF]

Earth-to-Mars distances vary from 60 to 400 million kilometers over a 14-year cycle. This complicates Mars mission design as a function of calendar time.
Woodcock, Gordon
core   +1 more source

Paleo‐Scours Within the Layered Sulfate‐Bearing Unit at Gale Crater, Mars: Evidence for Intense Wind Erosion [PDF]

Amelie L. Roberts, Sanjeev Gupta, Steven G. Banham, Aster Cowart, Lauren Edgar, W. Rapin, W. E. Dietrich, J. M. Davis, Edwin S. Kite, Gwénaël Caravaca, Claire A. Mondro, P. J. Gasda, J. R. Johnson, Stéphane Le Mouëlic, Deirdra M. Fey, A. B. Bryk, Gerhard Paar, Elizabeth S. Harris, A. A. Fraeman, A. R. Vasavada   +19 more
openalex   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

The search for an identification of amino acids, nucleobases and nucleosides in samples returned from Mars [PDF]

The Mars Sample Return mission will provide us with a unique source of material from our solar system; material which could advance our knowledge of the processes of chemical evolution. As has been pointed out, Mars geological investigations based on the
Gehrke, Charles W., Kuo, Kenneth C., Ponnamperuma, Cyril, Stalling, David L., Zumwalt, Robert W.   +4 more
core   +1 more source

What next for Mars? [PDF]

, 2008

openalex   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source