Results 91 to 100 of about 156,991 (333)

Overview of Ka-band communications technology requirements for the space exploration initiative [PDF]

open access: yes
In the Space Exploration Initiative, Ka-band frequencies are likely to carry the bulk of the communications traffic both in the vicinity of and on the return links from the moon and Mars.
Miller, Edward F.
core   +1 more source

Electrical pulse stimulation reflecting the episodic nature of real‐life exercise modulates metabolic and secretory profile of primary human myotubes

open access: yesFEBS Open Bio, EarlyView.
Here, we introduced an intermittent electrical stimulation protocol mimicking the episodic nature of real‐life exercise in vitro by alternating low‐ and high‐frequency stimulation. In comparison with widely used continuous stimulation, it enhanced the rate of glucose and fatty acid oxidation, but not the myokine release.
Klára Gabrišová   +11 more
wiley   +1 more source

Capabilities Development: From International Space Station and the Moon to Mars [PDF]

open access: yes
The President of the United States, in signing Space Policy Directive-1, directed the NASA Administrator to lead an innovative and sustainable program of exploration with commercial and international partners to enable human expansion across the solar ...
Boggs, Kathleen Gallagher   +2 more
core   +1 more source

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

open access: yesFEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti   +8 more
wiley   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Planetary science questions for the manned exploration of Mars [PDF]

open access: yes
A major goal of a manned Mars mission is to explore the planet and to investigate scientific questions for which the intensive study of Mars is essential. The systematic exploration of planets was outlined by the National Academy of Science.
Blanchard, Douglas P.
core   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Limits on Optical Counterparts to the Repeating Fast Radio Burst 20180916B from High-speed Imaging with Gemini-North/‘Alopeke

open access: yesThe Astrophysical Journal
We report on contemporaneous optical observations at ≈10 ms timescales from the fast radio burst (FRB) 20180916B of two repeat bursts (FRB 20201023 and FRB 20220908) taken with the ‘Alopeke camera on the Gemini-North telescope.
Charles D. Kilpatrick   +9 more
doaj   +1 more source

NASA's Chemical Transfer Propulsion Program for Pathfinder [PDF]

open access: yes
Pathfinder is a research and technology project, with specific deliverables, initiated by the National Aeronautics and Space Administration (NASA) which will strengthen the technology base of the United States civil space program in preparation for ...
Berkopec, Frank D.   +2 more
core   +1 more source

Expert consensus on research paradigms and technological layout for clinical priority diseases in traditional Chinese medicine: Rheumatoid arthritis

open access: yesAdvanced Chinese Medicine, EarlyView.
Abstract Rheumatoid arthritis (RA) is a chronic, highly disabling autoimmune disease. Although modern medical treatments have made progress, challenges such as suboptimal efficacy, relapse, difficulties in comorbidity management, and side effects persist.
Dier Jin   +8 more
wiley   +1 more source

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