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Angiotensin metabolites can stimulate receptors of the Mas-related genes family
Molecular and Cellular Biochemistry, 2008The Mas protooncogene encodes a G protein-coupled receptor, we identified, also by using the specific angiotensin-(1-7) antagonist A-779, to be associated with intracellular signaling of the angiotensin (Ang) II metabolite Ang-(1-7). Recently, Mas-related genes (Mrg) have been identified coding for the Mrg-receptor family. All family members share high
Florian, Gembardt +4 more
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Receptor Mas Protects Mice Against Hypothermia and Mortality Induced By Endotoxemia
Shock, 2014The renin-angiotensin (Ang) system is involved in maintaining cardiovascular function by regulating blood pressure and electrolyte homeostasis. More recently, alternative pathways within the renin-angiotensin system have been described, such as the ACE-2/Ang-(1-7)/Mas axis, with opposite effects to the ones of the ACE/Ang-II/AT1 axis.
Laura L, Souza +7 more
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Abstract P237: The At2 Receptor Agonist, C21, Can Also Stimulate Mas and Mrgd Receptors
Hypertension, 2017Background: It is well accepted that Compound 21 (C21) is a highly selective non-peptide angiotensin AT2 receptor agonist. C21 as well as angiotensin (Ang)-(1-7) have cardiovascular protective effects and are opponents of the often detrimental Ang II within the renin-angiotensin system.
Anja Tetzner +5 more
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Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-Vornhagen +2 more
exaly
Current treatment and recent progress in gastric cancer
Ca-A Cancer Journal for Clinicians, 2021Smita S Joshi, Brian D Badgwell
exaly
P17 AN ORAL mas-RECEPTOR AGONIST DECREASES PORTAL PRESSURE
Journal of Hepatology, 2014S. Klein +6 more
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