Results 121 to 130 of about 17,128 (260)

Lipocalin 13 Mitigates Metabolic Dysfunction-Associated Steatotic Liver Disease Through Inhibiting the ADRB2/ERK Signalling Pathway. [PDF]

Liver Int
Qin X, Hong Y, Ren W, Lei G, Zhou W, Wu S, Lin Z, Tan Y, Cao K, Wei Z, Shi H, Zhu X, Wei G.   +12 more
europepmc   +1 more source

Psychological Stress Promotes Tumor Growth in Hepatocellular Carcinoma Models Through Myeloid Signaling

Cancer Science, EarlyView.
Psychological stress promotes hepatocellular carcinoma progression through coordinated regulation of macrophages and neutrophils. Noradrenaline activates ADRB2 signaling in intratumoral macrophages, leading to CXCL2 production and neutrophil recruitment.
Keita Ogawa, Takahiro Aoki, Tatsuya Kaneko, Hongxuan Wang, Daiki Shimizu, Daisuke Katsumi, Iori Kojima, Hidekazu Tanaka, Kiwamu Motoyoshi, Ko Ozaki, Katsuhiro Nishimura, Tomohisa Iinuma, Mariko Takami, Shinichiro Motohashi   +13 more
wiley   +1 more source

Liver Organoids: From Disease Modelling to Regenerative Medicine

Cell Proliferation, EarlyView.
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang, Xiaotian Qu, Jinhong Si, Junkang Meng, Ting Zhang, Shuliang Niu   +5 more
wiley   +1 more source

Association of Hematological Biomarkers of Inflammation with 10-Year Major Adverse Cardiovascular Events and All-Cause Mortality in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease: The ARIC Study

Journal of Inflammation Research
Jia-Jie Wang, Zhichao Zheng, Ying Zhang Department of Cardiology, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, People’s Republic of ChinaCorrespondence: Ying Zhang, Department of ...
Wang JJ, Zheng Z, Zhang Y
doaj  

Modelling the impact of physical activity on MASLD in Saudi Arabia. [PDF]

PLoS One
Wallace C, Alessy SA, Abaalkhail F, Alghamdi S, Alfadda AA, Al Qabbani A, Alkhattabi F, AlAhmed RS, Mazi TA, Alghamdi H, Aldarwesh S, Alashmali S, Bawaked RA, Alobthani K, Al-Judaibi B, Al-Hamoudi WK, Raptis DA, Eurich B, Razavi H, Zivotic P, Rakic S, Cetinkaya V, Alqahtani SA.   +22 more
europepmc   +1 more source

Efficacy and Safety of SGLT2 Inhibitors in Patients With Genetic Lipodystrophy: A Real‐Life Experience From a National Reference Network

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim Lipodystrophy syndromes are rare diseases with metabolic and cardiovascular consequences. This study explores the metabolic and renal effects of sodium‐glucose cotransporter 2 inhibitors (SGLT2i) in patients with genetic lipodystrophy. Patients and Methods Patients with familial partial lipodystrophy (n = 57) or congenital generalised ...
Léna Robert, Ines Belalem, Corinne Vigouroux, Hippolyte Dupuis, Marie Christine Vantyghem, Mathilde Simonson, Estelle Nobecourt, Héléna Mosbah, Sophie Beliard, Stéphanie Jellimann, Sonja Janmaat, Camille Vatier, Sophie Lamothe   +12 more
wiley   +1 more source

Association between HOMA-IR and coexisting MASLD and type 2 diabetes: Insights from NHANES and network pharmacology. [PDF]

Ther Adv Endocrinol Metab
Heng XP, Yang LQ, Chen QW, Jin LX, Li YW, Ruan Y, Han Z, Yao SH, Hong XM, Wang ZT, Li L, He WD.   +11 more
europepmc   +1 more source

Circadian metabolic dysfunction in MASLD: Physiological insights and future directions. [PDF]

J Diabetes Investig
Journal of Diabetes Investigation, EarlyView.
Hwang YC.
europepmc   +2 more sources

Dyslipidaemia, Chronic Kidney Disease and Diabetes Mellitus: A Triple Threat to Cardiovascular Health

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Diabetes mellitus (DM) and chronic kidney disease (CKD) frequently coexist and together create a ‘triple threat’ with dyslipidaemia, enhancing the risk for cardiovascular morbidity and mortality. Diabetic kidney disease (DKD) leads to altered lipid metabolism through insulin resistance, inflammation and oxidative stress resulting in an ...
Ann S. Forrest, Priyanka Majety, Stéphanie B. Mayer, Om P. Ganda   +3 more
wiley   +1 more source

Gene-Based Clustering Identifies QSOX1 and IL1RAP as Biomarkers of Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]

Liver Int
Ma W, Huang J, Cai B, Shao M, Yu X, Kjær MB, Lv M, Zhong X, Xu S, Zhan B, Li Q, Huang Q, Ma M, Cheng L, Luo Y, Grønbæk H, Zhou X, Lin L.   +17 more
europepmc   +1 more source