Results 71 to 80 of about 743,584 (263)

EVOLUTION OF THE MERGER-INDUCED HYDROSTATIC MASS BIAS IN GALAXY CLUSTERS [PDF]

open access: yesThe Astrophysical Journal, 2012
In this work, we examine the effects of mergers on the hydrostatic mass estimate of galaxy clusters using high-resolution Eulerian cosmological simulations. We utilize merger trees to isolate the last merger for each cluster in our sample and follow the time evolution of the hydrostatic mass bias as the systems relax.
Nelson, Kaylea   +3 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Examining validity of body mass index calculated using height and weight data from the US driver license

open access: yesBMC Public Health, 2019
Background Driver license departments in many US states collect data on individuals’ height and weight. These data can be useful to researchers in epidemiological and public health studies.
Alla Chernenko   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A New Measure of Assembly Bias Using the Environment Dependence of the Luminosity Function

open access: yesThe Astrophysical Journal
Assembly bias is the variation in the clustering of dark matter halos and galaxies that arises from correlations between the halo assembly history and the large-scale environment at fixed halo mass.
Yikun Wang   +4 more
doaj   +1 more source

Hydrostatic Equilibrium Mass Bias: Simulations

open access: yes, 2017
Galaxy Clusters Accros Cosmic Times : invited ...
openaire   +2 more sources

MASS: Overcoming Language Bias in Image-Text Matching

open access: yesProceedings of the AAAI Conference on Artificial Intelligence
Pretrained visual-language models have made significant advancements in multimodal tasks, including image-text retrieval. However, a major challenge in image-text matching lies in language bias, where models predominantly rely on language priors and neglect to adequately consider the visual content. We thus present Multimodal ASsociation Score (MASS),
Jiwan Chung   +3 more
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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