Results 21 to 30 of about 643,213 (261)

Mass drug administration targeting Onchocerca volvulus in Owabi catchment area in Ashanti Region, Ghana: Determinants of drug coverage and drug uptake.

Parasite Epidemiology and Control, 2022
Introduction: Achieving high Mass Drug Administration (MDA) coverage and drug uptake are pivotal in the efforts to eradicate onchocerciasis. The present study investigated the extent and predictors of ivermectin MDA coverage and uptake from the ...
Francis Adjei Osei, Sam Newton, Isaac Nyanor, Eugene Osei-Yeboah, Evans Xorse Amuzu, Nicholas Karikari Mensah, Obed Ofori Nyarko, Ernest Amanor, Stephanie Boadi, Ophebia Asare, Samuel Frimpong Odoom, Peter Furu, Ellis Owusu-Dabo, Dan Wolf Meyrowitsch   +13 more
doaj   +1 more source

Socio-Cultural Factors that Influence Adherence to Mass Drug Administration among Schoolchildren in Schistosomiasis Hotspots along Lake Albert, Hoima District

Odoi P, Neema S, Bateganya F, Vennervald BJ, Wilson S.   +4 more
europepmc   +2 more sources

Adherence to mass drug administration and environmental factors related to lymphatic filariasis incidence: A case-control study in endemic area, Papua, Indonesia. [PDF]

Narra J
Wayangkau EC, Budiyono B, Raharjo M, Martini M.   +3 more
europepmc   +3 more sources

A study on coverage, compliance and awareness about mass drug administration for elimination of lymphatic filariasis in a district of West Bengal, India [PDF]

Journal of Vector Borne Diseases, 2011
P. Ray Karmakar, K. Mitra, Anirban Chatterjee, P.K. Jana, S. Bhattacharya & S.K. Lahiri
doaj   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

How well do coverage surveys and programmatically reported mass drug administration coverage match? Results from 214 mass drug administration campaigns in 15 countries, 2008–2017

BMJ Global Health, 2023
Introduction Delivering preventive chemotherapy through mass drug administration (MDA) is a central approach in controlling or eliminating several neglected tropical diseases (NTDs).
Karsor Kollie, Nebiyu Negussu, Scott D Nash, Donal Bisanzio, Fiona M Fleming, Pamela S Mbabazi, Richard Reithinger, Kathryn L Zoerhoff, Katherine Gass, John Kraemer, Brian B Fuller, Lynsey Blair, Roland Bougma, Aboulaye Meite, Bizuayehu Gashaw, Nana-Kwadwo Biritwum, Jean Frantz Lemoine, Helena Ullyartha Pangaribuan, Eksi Wijayanti, Clara Fabienne Rasoamanamihaja, Lazarus Juziwelo, Square Mkwanda, Pradip Rimal, Issa Gnandou, Bocar Diop, Ameyo Monique Dorkenoo, Rachel Bronzan, Edridah Muheki Tukahebwa, Fatima Kabole, Violetta Yevstigneyeva, Lauren Courtney, Joseph Koroma, Egide Endayishimye, Margaret C Baker   +33 more
doaj   +1 more source

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Comparison of coverage and compliance of mass drug administration 2017 in urban & rural areas of Valsad district, Gujarat, India

Journal of Integrated Health Sciences, 2017
Context: Filariasis, an infectious tropical disease is a major public health problem in India but remains neglected. This study was conducted with an objective to evaluate and compare the coverage and compliance of Mass Drug Administration (MDA) and ...
Anupam Verma, Rachna Prasad, N B Patel, R K Bansal   +3 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source