Results 21 to 30 of about 1,239,019 (334)

Longitudinal Analysis of Antibody Responses to Trachoma Antigens Before and After Mass Drug Administration. [PDF]

, 2014
Blinding trachoma, caused by the bacteria Chlamydia trachomatis, is a neglected tropical disease targeted for elimination by 2020. A major component of the elimination strategy is mass drug administration (MDA) with azithromycin.
Dize, Laura, Gaydos, Charlotte, Goodhew, Erica Brook, Lammie, Patrick J, Martin, Diana L, Mkocha, Harran, Morgan, Sheri Maria, Munoz, Beatriz, Switzer, Andrew J, West, Sheila K, Wiegand, Ryan E   +10 more
core   +14 more sources

Antimalarial mass drug administration: ethical considerations [PDF]

International Health, 2016
Falciparum malaria is a major cause of death and illness in tropical countries, particularly in childhood. In endemic countries, a significant proportion of the community is infected with malaria asymptomatically. One promising way to eliminate malaria is to give the entire population malaria treatment. This is called mass drug administration (MDA) and
Cheah, PY, White, NJ
openaire   +2 more sources

Mass drug administration of azithromycin: an analysis

Clinical Microbiology and Infection, 2023
WHO recommends mass drug administration (MDA) of the antibiotic azithromycin for children aged 1-11 months in areas with high rates of infant and child mortality. Notwithstanding the substantial potential benefits of lowering childhood mortality, MDA raises understandable concerns about exacerbating antibiotic resistance.In this study, we aimed to ...
Rebecca, Kahn, Nir, Eyal, Samba O, Sow, Marc, Lipsitch   +3 more
openaire   +2 more sources

Mass drug administration: the importance of synchrony [PDF]

Mathematical Medicine and Biology: A Journal of the IMA, 2016
Mass drug administration, a strategy in which all individuals in a population are subject to treatment without individual diagnosis, has been recommended by the World Health Organization for controlling and eliminating several neglected tropical diseases, including trachoma and soil-transmitted helminths.
Gao, Daozhou, Lietman, Thomas M, Dong, Chao-Ping, Porco, Travis C   +3 more
openaire   +4 more sources

Antimalarial mass drug administration in large populations and the evolution of drug resistance.

PLOS Global Public Health, 2023
Mass drug administration (MDA) with antimalarials has been shown to reduce prevalence and interrupt transmission in small populations, in populations with reliable access to antimalarial drugs, and in populations where sustained improvements in diagnosis
Tran Dang Nguyen, Thu Nguyen-Anh Tran, Thu Nguyen-Anh Tran, Daniel M Parker, Nicholas J White, Maciej F Boni   +5 more
doaj   +1 more source

The Impact of Mass Drug Administration on Lymphatic Filariasis

Journal of Tropical Medicine, 2022
Mass drug administration (MDA) has made a significant impact on the control of lymphatic filariasis (LF) since the establishment of the Global Programme to Eliminate Lymphatic Filariasis. However, its implementation is associated with several challenges,
Isaac Frimpong Aboagye, Yvonne Abena Afadua Addison   +1 more
doaj   +1 more source

Will mass drug administration eliminate lymphatic filariasis? Evidence from northern coastal Tanzania [PDF]

, 2012
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and 85 reproduction in any medium, provided the original author and source
Giles, Malecela, Malecela, McCarthy, MELISSA PARKER, Mohammed, Parker, Renne, TIM ALLEN, White   +9 more
core   +3 more sources

Role of mass drug administration in elimination of Plasmodium falciparum malaria: a consensus modelling study

The Lancet Global Health, 2017
Background: Mass drug administration for elimination of Plasmodium falciparum malaria is recommended by WHO in some settings. We used consensus modelling to understand how to optimise the effects of mass drug administration in areas with low malaria ...
Oliver J Brady, DPhil, Hannah C Slater, PhD, Peter Pemberton-Ross, PhD, Edward Wenger, PhD, Richard J Maude, MD, Prof Azra C Ghani, PhD, Melissa A Penny, PhD, Jaline Gerardin, PhD, Prof Lisa J White, PhD, Nakul Chitnis, PhD, Ricardo Aguas, PhD, Simon I Hay, DSc, Prof David L Smith, PhD, Erin M Stuckey, PhD, Emelda A Okiro, PhD, Prof Thomas A Smith, PhD, Dr Lucy C Okell, PhD   +16 more
doaj   +1 more source

A multi-center, open-labeled, cluster-randomized study of the safety of double and triple drug community mass drug administration for lymphatic filariasis [PDF]

, 2018
BackgroundThe Global Programme to Eliminate Lymphatic Filariasis (GPELF) provides antifilarial medications to hundreds of millions of people annually to treat filarial infections and prevent elephantiasis.
Gary J. Weil, Joshua Bogus, Michael Christian, Christine Dubray, Yenny Djuardi, Peter Fischer, Charles W. Goss, Myra Hardy, P Jambulingam, Christopher L. King, Vijesh Sridhar Kuttiat, Kaliannagounder Krishnamoorthy, Moses Laman, Jean Frantz Lemoine, Katiuscia O’Brian, Leanne J. Robinson, Josaia Samuela, Kenneth B. Schechtman, Anita D. Sircar, Adinarayanan Srividya, Andrew C. Steer, Taniawati Supali, Swaminathan Subramanian   +22 more
core   +8 more sources

Cost and community acceptability of enhanced antibiotic distribution approaches for trachoma in the Republic of South Sudan: enhancing the A in SAFE (ETAS) study protocol

BMC Ophthalmology, 2023
Background The World Health Organization targeted trachoma for global elimination as a public health problem by 2030. Reaching elimination thresholds by the year 2030 in the Republic of South Sudan will be a considerable challenge, as the country ...
Angelia M. Sanders, Samuel Makoy, Andrew R. Deathe, Stephen Ohidor, Timothy C. Jesudason, Andrew W. Nute, Patrick Odongi, Lochebe Boniface, Stella Abuba, Alexis S. Delahaut, Wilson Sebit, James Niquette, E. Kelly Callahan, Damian G. Walker, Scott D. Nash   +14 more
doaj   +1 more source