Multidrug-resistant malaria and the impact of mass drug administration
Janie Anne Zuber, Shannon Takala-Harrison Division of Malaria Research, Institute for Global Health, University of Maryland School of Medicine, Baltimore, MD, USA Abstract: Based on the emergence and spread throughout the Greater Mekong Subregion (GMS ...
Zuber JA, Takala-Harrison S
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Antimalarial mass drug administration in large populations and the evolution of drug resistance. [PDF]
Mass drug administration (MDA) with antimalarials has been shown to reduce prevalence and interrupt transmission in small populations, in populations with reliable access to antimalarial drugs, and in populations where sustained improvements in diagnosis
Tran Dang Nguyen +5 more
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Serology for trachoma surveillance after cessation of mass drug administration. [PDF]
BackgroundTrachoma, caused by Chlamydia trachomatis (Ct), is the leading infectious cause of blindness worldwide. Yearly azithromycin mass drug administration (MDA) plays a central role in efforts to eliminate blinding trachoma as a public health problem.
Diana L Martin +13 more
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Diffusion of treatment in social networks and mass drug administration [PDF]
Mass drug administration depends on the distributors’ contact with community members. Using data of deworming treatment distribution from Ugandan villages, the authors show that community medicine distributors with tightly-knit friendship connections ...
Goylette F. Chami +6 more
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Elimination of lymphatic filariasis: current perspectives on mass drug administration
John O Gyapong,1 Irene O Owusu,2 Frances B da-Costa Vroom,3 Ernest O Mensah,4 Margaret Gyapong5 1Centre for Neglected Tropical Diseases Research, Institute of Health Research, University of Health and Allied Sciences, Ho, 2Department of Epidemiology ...
Gyapong JO +4 more
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Mass drug administration for malaria [PDF]
Studies evaluating mass drug administration (MDA) in malarious areas have shown reductions in malaria immediately following the intervention. However, these effects vary by endemicity and are not sustained. Since the 2013 version of this Cochrane Review on this topic, additional studies have been published.Primary objectives To assess the sustained ...
Shah, Monica P +5 more
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Applications of human microdosing with accelerator mass spectrometry: assessment of ability to predict drug-drug interactions and determine the pharmacokinetics of enantiomers [PDF]
In this thesis, new applications of microdosing were explored in two clinical trials. Methods were developed for the separation and quantification of 14C-labelled analytes in human plasma using two-dimensional HPLC and accelerator mass ...
Croft, M L
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Mass drug administration for malaria [PDF]
Mass drug administration (MDA), defined as the empiric administration of a therapeutic antimalarial regimen to an entire population at the same time, has been a historic component of many malaria control and elimination programmes, but is not currently recommended.
Poirot, Eugenie +5 more
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Mass drug administration: the importance of synchrony [PDF]
Mass drug administration, a strategy in which all individuals in a population are subject to treatment without individual diagnosis, has been recommended by the World Health Organization for controlling and eliminating several neglected tropical diseases, including trachoma and soil-transmitted helminths.
Gao, Daozhou +3 more
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Assessing the impact of a missed mass drug administration in Haiti. [PDF]
Lymphatic filariasis (LF) is a disfiguring and debilitating parasitic disease that is endemic in 81 countries, placing a staggering 1.3 billion people at risk for filarial infection [1]. In 1997, the World Health Assembly resolved to eliminate LF as a public health problem, and in 2000, the Global Programme to Eliminate Lymphatic Filariasis (GPELF) was
Kimberly Y Won +4 more
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