Results 41 to 50 of about 7,151,878 (288)

Mass Drug Administration of Triclabendazole for Fasciola Hepatica in Bolivia [PDF]

The American Journal of Tropical Medicine and Hygiene, 2019
Human infection with Fasciola hepatica leads to obstruction of the common bile duct by adult worms and disease characterized by biliary colic, epigastric pain, and nausea. Recommended treatment is a single dose of triclabendazole (TCBZ) (10 mg/kg).
Sergio, Mollinedo, Patricia, Gutierrez, Rosa, Azurduy, Freddy, Valle, Alejandra, Salas, Zoraida, Mollinedo, Paula, Soto, Cleye F, Villarroel, Janet, Ransom, Robb, Lawrence, Jonathan, Berman, Jaime, Soto   +11 more
openaire   +2 more sources

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

Mass drug administration targeting Onchocerca volvulus in Owabi catchment area in Ashanti Region, Ghana: Determinants of drug coverage and drug uptake.

Parasite Epidemiology and Control, 2022
Introduction: Achieving high Mass Drug Administration (MDA) coverage and drug uptake are pivotal in the efforts to eradicate onchocerciasis. The present study investigated the extent and predictors of ivermectin MDA coverage and uptake from the ...
Francis Adjei Osei, Sam Newton, Isaac Nyanor, Eugene Osei-Yeboah, Evans Xorse Amuzu, Nicholas Karikari Mensah, Obed Ofori Nyarko, Ernest Amanor, Stephanie Boadi, Ophebia Asare, Samuel Frimpong Odoom, Peter Furu, Ellis Owusu-Dabo, Dan Wolf Meyrowitsch   +13 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Review of Mass Drug Administration for Malaria and Its Operational Challenges [PDF]

The American Society of Tropical Medicine and Hygiene, 2015
Mass drug administration (MDA) was a component of many malaria programs during the eradication era, but later was seldomly deployed due to concerns regarding efficacy and feasibility and fear of accelerating drug resistance. Recently, however, there has been renewed interest in the role of MDA as an elimination tool.
Newby, Gretchen, Hwang, Jimee, Koita, Kadiatou, Chen, Ingrid, Greenwood, Brian, Von Seidlein, Lorenz, Shanks, G. Dennis, Slutsker, Laurence, Kachur, S. Patrick, Wegbreit, Jennifer, Ippolito, Matthew M., Poirot, Eugenie, Gosling, Roly   +12 more
openaire   +5 more sources

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Impact of glucuronide interferences on therapeutic drug monitoring of posaconazole by tandem mass spectrometry [PDF]

, 2010
Background: Posaconazole is a novel antifungal drug for oral application intended especially for therapy of invasive mycoses. Due to variable gastrointestinal absorption, adverse side effects, and suspected drug-drug interactions, therapeutic drug ...
Michael Vogeser, Karl J. Lackner, Burghardt, Stephan, Lackner, Karl J., Vogelsberger, Rita, Krueger, Ralf, Stephan Burghardt, Vogeser, Michael, Rita Vogelsberger, Ralf Krüger   +9 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Ivermectin as Mass Drug Administration for Scabies – The Need of the Hour

Indian Journal of Public Health
Scabies is a highly transmissible disease caused by the mite, Sarcoptes scabiei var. hominis. Although any age group can be affected, it is common in children.
Satyaki Ganguly, Parul Verma, P. Narsimha Rao, Anup Kumar Tiwary, Chandrakant Ramchandra Revankar, V. Ramesh, Sudipta Roy   +6 more
doaj   +1 more source

Awareness of and participation in mass drug administration programs used for onchocerciasis control in the Atwima Nwabiagya North District, Ghana

Global Health Research and Policy, 2023
Background Studies on Mass drug administration (MDA) in Ghana targeting various diseases, have mostly focused on factors that affect coverage and compliance to MDA with limited focus on evidence regarding awareness and community perception of the program.
Francis Adjei Osei, Sam Kofi Tekyi Newton, Isaac Nyanor, Eugene Osei-Yeboah, Evans Xorse Amuzu, Nicholas Karikari Mensah, Obed Ofori Nyarko, Ernest Amanor, Samuel Frimpong Odoom, Suraj Yawnumah Abubakar, Mathias Dongyele, Aliyu Mohammed, Ofeibea Asare, Stephanie Boadi, Peter Furu, Dan Wolf Meyrowitsch, Ellis Owusu-Dabo   +16 more
doaj   +1 more source