Results 61 to 70 of about 7,151,878 (288)
The impact of mass drug administration of antibiotics on the gut microbiota of target populations
Infectious Diseases of Poverty, 2022 Antibiotics have become a mainstay of healthcare in the past century due to their activity against pathogens. This manuscript reviews the impact of antibiotic use on the intestinal microbiota in the context of mass drug administration (MDA).
Ethan K. Gough
doaj +1 more source
Mass drug administration unit cost (US$).
, 2022 Mass drug administration unit cost (US$).
Lucia Romani (698633) +14 more
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Effectiveness of azithromycin mass drug administration on trachoma: a systematic review
Chinese Medical Journal, 2021 Backgrounds:. Azithromycin mass drug administration (MDA) is a key part of the strategy for controlling trachoma. This systematic review aimed to comprehensively summarize the present studies of azithromycin MDA on trachoma; provide an overview of the ...
Tao Xiong +14 more
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Operational strategies of anti-malarial drug campaigns for malaria elimination in Zambia's southern province: a simulation study [PDF]
, 2016 BACKGROUND: Malaria elimination requires reducing both the potential of mosquitoes to transmit parasites to humans and humans to transmit parasites to mosquitoes. To achieve this goal in Southern province, Zambia a mass test and treat (MTAT) campaign was
Miller, John M. +9 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Health Science ReportsBackground The fight against schistosomiasis (urogenital and intestinal) has prolonged more than expected with more areas that were previously known to have less or no incidence of infection now recording alarming incidence rate.
Fatima Amponsah Fordjour +1 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Bulletin of the World Health Organization, 2007 OBJECTIVE: To determine the role of vector control in further decreasing the transmission of bancroftian filariasis achieved by mass drug administration and the long-term impact on filariometric indices.
IP Sunish +5 more
doaj
Mass drug administration should be implemented as a tool to accelerate elimination: against
Malaria Journal, 2019 In most malaria situations, mass drug administration (MDA) will result in a rapid reduction in the incidence and prevalence of malaria in the target population.
Kamini Mendis
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