Results 71 to 80 of about 7,151,878 (288)

Pharmacokinetics, feasibility and safety of co-administering azithromycin, albendazole, and ivermectin during mass drug administration: A review.

PLoS Neglected Tropical Diseases, 2023
IntroductionTraditionally, health ministries implement mass drug administration programmes for each neglected tropical disease (NTD) as separate and distinct campaigns.
Scott McPherson, Anthony W Solomon, Fikre Seife, Hiwot Solomon, Teshome Gebre, David C W Mabey, Michael Marks   +6 more
doaj   +1 more source

Ethics, economics, and the use of primaquine to reduce falciparum malaria transmission in asymptomatic populations. [PDF]

, 2014
Yoel Lubell and colleagues consider ethical and economic perspectives on mass drug administration of primaquine to limit transmission of P. falciparum malaria.
Richard J Maude, Maude, RJ, Arjen Dondorp, Michael Parker, Shunmay Yeung, Drake, Tom, Lisa White, White, Lisa, White, Nicholas J, Parker, M, Yeung, Shunmay, Day, NP, Nicholas P J Day, Drake, T, Yeung, S, Yoel Lubell, Day, Nicholas PJ, Varadan, S, White, L, Dondorp, A, Lubell, Y, Varadan, Sheila, Parker, Michael, Cheah, PY, Sheila Varadan, Nicholas J White, Dondorp, Arjen, Tom Drake, Day, Nicholas, White, NJ, Cheah, Phaik Yeong, White, Nicholas, Maude, Richard J, Lubell, Yoel, Phaik Yeong Cheah   +34 more
core   +1 more source

Survey and mass drug administration (MDA) timelines.

, 2023
Survey and mass drug administration (MDA) timelines.
Robert Butcher (2873378), Sarah Anne J. Guagliardo (6107906), Diana L. Martin (11037665), Sarah E. Gwyn (16510632), Anasaini Cama (12431933), Raebwebwe Taoaba (4429789), Ana Bakhtiari (4429780), Karana Wickens (16510638), Kab Tun (16510635), E. Brook Goodhew (16510629), Caleb D. Mpyet (14608546), Anthony W. Solomon (7348580), Rabebe Tekeraoi (4429786), Cristina Jimenez (11623377), Emma M. Harding-Esch (9223636)   +14 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Pharmacokinetics of hydroxymethylnitrofurazone and its parent drug nitrofurazone in rabbits

, 2013
The prodrug hydroximethylnitrofurazone (NFOH) presents antichagasic activity with greatly reduced toxicity compared to its drug matrix nitrofurazone (NF). Besides these new characteristics, the prodrug was more active against the parasite T.
Davanço, Marcelo Gomes [UNESP], Chin, Chung Man, Filho, Marco Antonio Ferraz Nogueira [UNESP], Padilha, Elias Carvalho, Campos, Michel Leandro de, de Campos, Michel Leandro [UNESP], Pestana, Kelly Christina [UNESP], Padilha, Elias Carvalho [UNESP], Chin, Chung Man [UNESP], Nogueira Filho, Marco Antonio Ferraz, Machado, Diego Vinicius de Pontes, Pestana, Kelly Christina, Peccinini, Rosângela Gonçalves [UNESP], de Pontes Machado, Diego Vinicius [UNESP], Davanço, Marcelo Gomes   +14 more
core   +4 more sources

Sero-epidemiological evaluation of malaria transmission in The Gambia before and after mass drug administration

BMC Medicine, 2020
Background As The Gambia aims to achieve malaria elimination by 2030, serological assays are a useful surveillance tool to monitor trends in malaria incidence and evaluate community-based interventions.
Lindsey Wu, Julia Mwesigwa, Muna Affara, Mamadou Bah, Simon Correa, Tom Hall, Susheel K. Singh, James G. Beeson, Kevin K. A. Tetteh, Immo Kleinschmidt, Umberto D’Alessandro, Chris Drakeley   +11 more
doaj   +1 more source

Mass drug administration for trachoma: how long is not long enough? [PDF]

PLoS Neglected Tropical Diseases, 2015
BACKGROUND:Blinding trachoma is targeted for elimination by 2020 using the SAFE strategy (Surgery, Antibiotics, Facial cleanliness, and Environmental improvements). Annual mass drug administration (MDA) with azithromycin is a cornerstone of this strategy.
Violeta Jimenez, Huub C Gelderblom, Rebecca Mann Flueckiger, Paul M Emerson, Danny Haddad   +4 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

An evaluation of coverage and compliance of mass drug administration 2006 for elimination of lymphatic filariasis in endemic areas of Gujarat

Indian Journal of Community Medicine, 2008
Background: Mass drug administration (MDA) means once-in-a-year administration of diethyl carbamazine (DEC) tablet to all people (excluding children under 2 years, pregnant women and severely ill persons) in identified endemic areas.
Kumar Pradeep, Prajapati P, Saxena Deepak, Kavishwar Abhay, Kurian George   +4 more
doaj  

Mass Drug Administration: Contextual Factor Considerations

The American Journal of Tropical Medicine and Hygiene
ABSTRACT. In designing mass drug administration (MDA) campaigns, it is imperative to consider contextual factors that affect uptake of the intervention, including acceptability, cost, feasibility, and health system considerations, to ensure optimal coverage.
Schneider, Zachary D., Busbee, Alexandra L., Boily, Marisa C., Shah, Monica P., Hwang, Jimee, Lindblade, Kim A., Gutman, Julie R.   +6 more
openaire   +2 more sources