Results 41 to 50 of about 1,239,019 (334)

The Population Biology and Transmission Dynamics of Loa loa [PDF]

, 2017
Endemic to Central Africa, loiasis – or African eye worm (caused by the filarial nematode Loa loa) – affects more than 10 million people. Despite causing ocular and systemic symptoms, it has typically been considered a benign condition, only of public ...
Basáñez, M-G, Boussinesq, M, Chesnais, C B, Pion, S D S, Walker, M, Whittaker, C   +5 more
core   +1 more source

Differential expression of skeletal muscle genes following administration of clenbuterol to exercised horses. [PDF]

, 2016
BackgroundClenbuterol, a beta2-adrenergic receptor agonist, is used therapeutically to treat respiratory conditions in the horse. However, by virtue of its mechanism of action it has been suggested that clenbuterol may also have repartitioning affects in
Chouicha, Nadira, Harrison, Linda M, Kass, Phil H, Knych, Heather K, Steinmetz, Stacy J   +4 more
core   +1 more source

Persistence of onchocerciasis in villages in Enugu and Ogun states in Nigeria following many rounds of mass distribution of ivermectin

BMC Infectious Diseases, 2022
Background Onchocerciasis is endemic in most local government areas (LGAs) in Enugu and Ogun states. Most meso- and hyper-endemic LGAs have received many rounds of ivermectin mass drug administration (MDA).
Uwem F. Ekpo, Obiora A. Eneanya, Edith N. Nwankwo, Islamiat Y. Soneye, Gary J. Weil, Peter U. Fischer, Obioma C. Nwaorgu   +6 more
doaj   +1 more source

Mass drug administration targeting Onchocerca volvulus in Owabi catchment area in Ashanti Region, Ghana: Determinants of drug coverage and drug uptake.

Parasite Epidemiology and Control, 2022
Introduction: Achieving high Mass Drug Administration (MDA) coverage and drug uptake are pivotal in the efforts to eradicate onchocerciasis. The present study investigated the extent and predictors of ivermectin MDA coverage and uptake from the ...
Francis Adjei Osei, Sam Newton, Isaac Nyanor, Eugene Osei-Yeboah, Evans Xorse Amuzu, Nicholas Karikari Mensah, Obed Ofori Nyarko, Ernest Amanor, Stephanie Boadi, Ophebia Asare, Samuel Frimpong Odoom, Peter Furu, Ellis Owusu-Dabo, Dan Wolf Meyrowitsch   +13 more
doaj   +1 more source

Anthropometric indices of Gambian children after one or three annual rounds of mass drug administration with azithromycin for trachoma control. [PDF]

, 2014
BACKGROUND: Mass drug administration (MDA) with azithromycin, carried out for the control of blinding trachoma, has been linked to reduced mortality in children.
A Amza, A Amza, A Sommer, A Weisz, AE Roth, AJ Weisz, Ansumana Sillah, C Nokes, C Panter-Brick, CG Victora, CJ Whitty, CL Coles, CL Coles, D Stare, David C W Mabey, EJ Giamarellos-Bourboulis, EK Gough, EM Harding-Esch, EM Harding-Esch, Emma M Harding-Esch, EV Basilion, I Udan, JD Keenan, JH Humphrey, John Hart, KL Kotloff, KN Ryan, L Leonor Rodríguez, LS Stephenson, Martin J Holland, MG Rowland, MG Rowland, MP Eccles, P Aaby, PG Lunn, R Goto, RL Guerrant, Robin L Bailey, S Haug, Sarah E Burr, T Edwards, Tansy Edwards, TC Porco, WHO, WHO, WHO, WHO   +46 more
core   +2 more sources

Mass campaigns with antimalarial drugs: a modelling comparison of artemether-lumefantrine and DHA-piperaquine with and without primaquine as tools for malaria control and elimination

, 2015
Antimalarial drugs are a powerful tool for malaria control and elimination. Artemisinin-based combination therapies (ACTs) can reduce transmission when widely distributed in a campaign setting.
Eckhoff, Philip, Gerardin, Jaline, Wenger, Edward A.   +2 more
core   +1 more source

Review of mass drug administration for malaria and its operational challenges. [PDF]

, 2015
Mass drug administration (MDA) was a component of many malaria programs during the eradication era, but later was seldomly deployed due to concerns regarding efficacy and feasibility and fear of accelerating drug resistance.
Chen, Ingrid, Gosling, Roly, Greenwood, Brian, Hwang, Jimee, Ippolito, Matthew M, Kachur, S Patrick, Koita, Kadiatou, Newby, Gretchen, Poirot, Eugenie, Shanks, G Dennis, Slutsker, Laurence, von Seidlein, Lorenz, Wegbreit, Jennifer   +12 more
core   +1 more source

Entomological impact of mass administration of ivermectin and dihydroartemisinin-piperaquine in The Gambia: a cluster-randomized controlled trial

Parasites & Vectors, 2022
Background Vector control interventions in sub-Saharan Africa rely on insecticide-treated nets and indoor residual spraying. Insecticide resistance, poor coverage of interventions, poor quality nets and changes in vector behavior threaten the ...
Harouna M. Soumare, Edgard Diniba Dabira, Muhammed M. Camara, Lamin Jadama, Pa Modou Gaye, Sainey Kanteh, Ebrima A. Jawara, Amie Kolleh Njie, Fatou Sanneh, Mamadou Ousman Ndiath, Steven W. Lindsay, Bakary Conteh, Sainey Ceesay, Nuredin Mohammed, Michael Ooko, John Bradley, Chris Drakeley, Annette Erhart, Teun Bousema, Umberto D’Alessandro   +19 more
doaj   +1 more source

Safety and Efficacy of Anticoagulation Therapy in Paediatric Patients With Solid Tumours or Lymphomas at Risk of Thrombocytopenia: A Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with solid tumours or lymphomas have an increased risk of thromboembolism (TE) and thrombocytopenia. Evidence‐based strategies for anticoagulation therapy (ACT) for patients with thrombocytopenia are limited. We examined the impact of thrombocytopenia on ACT administration and bleeding incidence in children with solid ...
Andrés Felipe Fajardo, Katherine Talpin, Bishal Harry, Uma H. Athale, Anthony K. C. Chan, Mihir D. Bhatt   +5 more
wiley   +1 more source

Reduced efficacy of praziquantel against Schistosoma mansoniis associated with multiple rounds of mass drug administration [PDF]

, 2016
Background: Mass drug administration (MDA) with praziquantel is the cornerstone of schistosomiasis control in sub-Saharan Africa. The effectiveness of this strategy is dependent on the continued high efficacy of praziquantel; however, drug efficacy is ...
Cotton, James A., Crellen, Thomas, Kabatereine, Narcis B., Lamberton, Poppy H.L., Tukahebwa, Edridah M., Walker, Martin, Webster, Joanne P.   +6 more
core   +5 more sources