Results 71 to 80 of about 11,477,062 (289)

Effect of Injection Pressure, Injection Duration, and Injection Frequency on Direct Injector’s Mass Flow Rate for Compressed Natural Gas Fuel

open access: yesMATEC Web of Conferences, 2018
A conventional gasoline direct injector is converted for gaseous fuel application. The conversion alters the injector characteristic which further affect the mixture formation and combustion processes.
Alias Mohamad Hafizul Rahman   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Choked Flow Characteristics of Subcritical Refrigerant Flowing Through Converging-Diverging Nozzles

open access: yesEntropy, 2014
This paper presents the experimental results the choked flow characteristics of a subcritical refrigerant through a converging-diverging nozzle. A test nozzle with a throat diameter of 2 mm was designed and developed.
Zhenying Zhang   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Optimizing the Mass Flow and Temperature Difference in a Cooling System for Energy Conservation

open access: yes, 1980
Conventional wisdom in recent times has been to raise the chilled water temperature to conserve chiller power. This is an effective and well-proven conservation strategy; however, it may be less optimal than other available alternatives. Reducing the fan
Hart, M. N., Bond, S. K.
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Wet Gas Flow Metering Technique Using a Venturi With Conductance Sensors [PDF]

open access: yes
Wet gas metering is becoming an increasingly important problem to the oil and gas industry. Much research has been done to measure the water and gas flow rates of two-phase flows using a Venturi meter.
Musbah, Abdurazzaq
core   +3 more sources

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