Results 61 to 70 of about 11,477,062 (289)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Tube Optimization for the Downhole Two Stage Series Hydrocyclone
In the study of oil-water separation performance of downhole hydrocyclone,the effect of string overflow channel on the separation performance has not been reported.Through study on the two-stage series hydrocyclone technology,the effect of the overflow ...
Zhao Lixin +3 more
doaj
Pressure Drop Characteristics of a Novel Active Liquid Feeding Evaporator
The application of enhanced tubes in an evaporator inevitably results in a higher pressure drop. Herein, a novel active liquid feeding evaporator is proposed to reduce the pressure drop by actively adjusting the mass flow rate and vapor quality along the
Li Junjie +6 more
doaj
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Experimental and Numerical Study on the Thermal Performance of a Water/Steam Cavity Receiver
An experimental platform was designed and built for testing the thermal performance of a water/steam cavity receiver. The experimental platform was utilized to investigate the start-up performance and operation characteristics of the receiver.
Jinjia Wei, Jiabin Fang, Nan Tu
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Mass-flow-rate-controlled fluid flow in nanochannels by particle insertion and deletion
A nonequilibrium molecular dynamics method to induce fluid flow in nanochannels, the insertion-deletion method (IDM), is introduced. IDM inserts and deletes particles within distinct regions in the domain, creating locally high and low pressures. The benefits of IDM are that it directly controls a physically meaningful quantity, the mass flow rate ...
Paul L, Barclay, Jennifer R, Lukes
openaire +3 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Mass observation / by Mass Observation.
Electronic reproduction. Canberra, A.C.T.
Mass-Observation.
core

