Results 81 to 90 of about 1,158,286 (309)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Internal mass and heat transfer between a single deformable droplet and simple extensional creeping flow

open access: yes, 2018
This work studied numerically the internal mass/heat transfer of a deformable droplet immersed in a simple extensional flow. The droplet would deform gradually from prolate spheroid to 'peanut' in uniaxial extensional flow, or from oblate spheriod to ...
Liu, Anjun   +4 more
core   +2 more sources

Choked Flow Characteristics of Subcritical Refrigerant Flowing Through Converging-Diverging Nozzles

open access: yesEntropy, 2014
This paper presents the experimental results the choked flow characteristics of a subcritical refrigerant through a converging-diverging nozzle. A test nozzle with a throat diameter of 2 mm was designed and developed.
Zhenying Zhang   +3 more
doaj   +1 more source

Optimizing the Mass Flow and Temperature Difference in a Cooling System for Energy Conservation

open access: yes, 1980
Conventional wisdom in recent times has been to raise the chilled water temperature to conserve chiller power. This is an effective and well-proven conservation strategy; however, it may be less optimal than other available alternatives. Reducing the fan
Hart, M. N., Bond, S. K.
core  

Surface effects in flow boiling of R134a in microtubes

open access: yes, 2011
This is the post-print version of the Article. The official published version can be accessed from the link below - Copyright @ 2011 ElsevierThe inner surfaces of microtubes may be influenced strongly by the process of making them due to manufacturing ...
Tassos G. Karayiannis   +5 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Flow rate measurement of rarefied binary gases in long rectangular microchannels

open access: yes, 2011
This paper was presented at the 3rd Micro and Nano Flows Conference (MNF2011), which was held at the Makedonia Palace Hotel, Thessaloniki in Greece.
Szalmas, L   +3 more
core  

Medição de vazão de escoamentos bifásicos utilizando tubo de Venturi ou placa de orifício associados a um sensor de fração de vazio com campo elétrico girante [PDF]

open access: yes, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Mecânica.A medição em tempo real das vazões mássicas em escoamentos bifásicos líquido-gás, sem a separação das fases, é a solução
Oliveira, Jorge Luiz Goes
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Tube Optimization for the Downhole Two Stage Series Hydrocyclone

open access: yesShiyou jixie, 2015
In the study of oil-water separation performance of downhole hydrocyclone,the effect of string overflow channel on the separation performance has not been reported.Through study on the two-stage series hydrocyclone technology,the effect of the overflow ...
Zhao Lixin   +3 more
doaj  

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