Results 131 to 140 of about 11,395,261 (251)

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Optimal prediction under asymmetric loss [PDF]

Prediction problems involving asymmetric loss functions arise routinely in many fields, yet the theory of optimal prediction under asymmetric loss is not well developed.
Francis X. Diebold, Peter F. Christoffersen   +1 more
core  

A Study on the Durability of Solidification Materials Based on Multi-Source Solid Waste Using Recycled Aggregates in Chemical Environments. [PDF]

Materials (Basel)
Ni J, Zhao Y, Jiang Q, Hu H, Ding H, Zhan Q.   +5 more
europepmc   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Forced Degradation Study of Vonoprazan Fumarate by HPLC and Characterisation of Its Degradation Products Using LC-QTOF-MS/MS. [PDF]

Rapid Commun Mass Spectrom
Bhatt N, Sonaje D, Samanthula G.
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Is dynamometry able to infer the risk of muscle mass loss in patients with COPD?

, 2015
Dionei Ramos,1 Giovana Navarro Bertolini,1 Marceli Rocha Leite,1 Luiz Carlos Soares Carvalho Junior,1 Paula Roberta da Silva Pestana,1 Vanessa Ribeiro dos Santos,2 Ana Claudia de Souza Fortaleza,2 Fernanda Maria Machado Rodrigues,1 Ercy Mara Cipulo ...
da Silva Pestana PR, Santos VR, Fortaleza ACS, Leite MR, Bertolini GN, Rodrigues FMM, Carvalho Junior LCS, Ramos D, Ramos EMC   +8 more
core  

Mass balance of the Greenland and Antarctic ice sheets from the 1970s to 2023. [PDF]

Sci Data
Otosaka IN, Shepherd A, Amory C, Horwath M, Ivins ER, King MD, Nowicki S, Payne AJ, Rignot E, Sørensen LS, Schlegel NJ, Simon KM, Smith BE, Sutterley TC, van den Broeke MR, Velicogna I, A G, Agosta C, Ditmar P, Döhne T, Engdahl ME, Fettweis X, Forsberg R, Gardner AS, Gilbert L, Goelzer H, Gourmelen N, Groh A, Hansen N, Harig C, Helm V, Khan SA, Kittel C, Langen PL, Larsen M, Loomis BD, McMillan M, Medley B, Melini D, Mottram RH, Muir A, Nilsson J, Noël B, Pattle ME, Roca I Aparici M, Sasgen I, Save HV, Scheuchl B, Schrama EJO, Schröder L, Seo KW, Simonsen SB, Slater T, Spada G, Vishwakarma BD, Wever N, Wiese DN, Wouters B.   +57 more
europepmc   +1 more source

A Low Psoas Muscle Index Was Associated With a Poorer Overall Survival in Patients Who Underwent Percutaneous Nephrostomy

Aging and Cancer, EarlyView.
In patients with malignant ureteral obstruction undergoing percutaneous nephrostomy, sarcopenia defined by a low psoas muscle index was independently associated with poor overall survival on multivariate Cox regression analysis, suggesting that preoperative assessment of psoas muscle index may aid prognostic stratification in this population.
Kota Shimokihara, Takashi Kawahara, Kazuhide Makiyama, Hiroji Uemura   +3 more
wiley   +1 more source

Recessions and the Cost of Job Loss [PDF]

We develop new evidence on the cumulative earnings losses associated with job displacement, drawing on longitudinal Social Security records for U.S. workers from 1974 to 2008.
Steven J. Davis, Till M. von Wachter
core