Results 111 to 120 of about 3,205,189 (299)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Impact of Various Erosive Environments on the Durability of POM Fiber-Reinforced Ultra-High-Performance Concrete

open access: yesBuildings
To address the durability challenges faced by traditional concrete in marine environments, this study focuses on polyoxymethylene (POM) fiber-reinforced ultra-high-performance concrete (PFUHPC) and, for the first time, systematically investigates the ...
Jingliang Dong   +6 more
doaj   +1 more source

Period – mass-loss rate relation of Miras with and without technetium [PDF]

open access: yesAstronomy & Astrophysics, 2013
Aims: We report the discovery that Mira variables with and without absorption lines of the element technetium (Tc) occupy two different regions in a diagram of near- to mid-infrared colour versus pulsation period. Tc is an indicator of a recent or ongoing mixing event called the third dredge-up (3DUP), and the near- to mid-IR colour, such as the (K-[22]
openaire   +4 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Effect of Iron Tailings Powder on the Mechanical Properties and Calcium Hydroxide Content in Limestone Powder Concrete

open access: yesKuangchan zonghe liyong
This is an article in the field of ceramics and composites. Influence of the mixed mineral powder content and proportion on the performance of concrete were studied.
Jujing ZHANG, Dongshen HUA
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Relationships Between Ultrasonic-Based Elastic Modulus Loss, Mass Loss and Strength Loss in Two Hardwoods Commonly Used in Northern Chinese Timber Heritage

open access: yesBuildings
Assessing decay-induced mechanical deterioration in hardwood components is essential for the conservation of northern Chinese timber heritage, where structural members such as the Dou and Gong have been exposed to complex environments for centuries ...
Panpan Liu   +4 more
doaj   +1 more source

A Porosity-Length Formalism for Photon-Tiring-Limited Mass Loss from Stars Above the Eddington Limit

open access: yes, 2004
We examine radiatively driven mass loss from stars near and above the Eddington limit (Ledd). We begin by reviewing the instabilities that are expected to form extensive structure near Ledd.
Gayley, Kenneth G.   +2 more
core   +1 more source

Supernovae: Little Bear's mass loss rate [PDF]

open access: yesNature, 1985
H6 influx of shallow-water carbonate debris, a rapid reduction in the amount of pelagic carbonate and a period of slow or con- densed sedimentation; it is followed by the onset of accumulation of carbonate- poor bioturbated clay containing organic- rich layers (black shales).
openaire   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Home - About - Disclaimer - Privacy