Results 181 to 190 of about 1,701,812 (348)

The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity

FEBS Open Bio, EarlyView.
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda, Melissa Montrose, Akinori Takahashi, Risa Ishida, Sandrine Burriel, Nao Ohmine, Tohru Natsume, Shungo Adachi, Minsoo Kim, Tadashi Yamamoto   +9 more
wiley   +1 more source

Real-Time Risk Score for Glaucoma Mass Screening by Spectral Domain Optical Coherence Tomography: Development and Validation. [PDF]

Transl Vis Sci Technol, 2022
Fukai K, Terauchi R, Noro T, Ogawa S, Watanabe T, Nakagawa T, Honda T, Watanabe Y, Furuya Y, Hayashi T, Tatemichi M, Nakano T.   +11 more
europepmc   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Relevance of cycle threshold values in mass screening by reverse-transcription-PCR during COVID-19 pandemic in Belgium: a decision-making support? [PDF]

Future Virol, 2022
Dufour P, Paridaens H, Senterre JM, Minon JM.   +3 more
europepmc   +1 more source

Effect of Mass Screening for Breast Cancer from the Aspect of Psychosocial Assessment of the Quality of Life [PDF]

, 1993
Takao Yokoe, Tsunehiro Ishida, Suketami Tominaga, Tetsuo Kuroishi, Tadaoki Morimoto, Hideya Tashiro, Sueyoshi Itoh, Rikiya Abe, Jun Ota, Toshio Horino, T Taguchi, Kazuyoshi Honda, Michizou Sasakawa, Yoshitomo Kashiki, Satoru Yamamoto, Kohji Enomoto, Masami Ogita, Koichi Yoshida, C Kido, Mamoru Fukuda, Hiromu Watanabe, M Izuo   +21 more
openalex   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Mass Screening for Primary Open-Angle Glaucoma: Is It Really Relevant? [PDF]

Cureus
Razzak A, Bouazza M, Mouhib L, Khamaily M, Elbelhadji M.   +4 more
europepmc   +1 more source

Mass screening of urine in school children.

, 1976
Katsuyoshi Murakami
openalex   +2 more sources

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

FEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson, Lisa Lif, Husam Oda, Alexandra Lorenzzi de Melo, David Lindquist, Håkan Hedman   +5 more
wiley   +1 more source

Effectiveness of single-target fecal DNA methylation test in regional mass screening for colorectal cancer and precancerous lesions in China. [PDF]

Gastroenterol Rep (Oxf)
Kong X, Wu Q, Zhang Z, Yu Z, Niu F, Wang X, Zou H.   +6 more
europepmc   +1 more source