Results 91 to 100 of about 2,327,164 (344)

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis

open access: yesMolecular Oncology, EarlyView.
Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch   +11 more
wiley   +1 more source

Few remarks on the mass spectrum of two-dimensional Toda lattice of $E_8$ type [PDF]

open access: yesarXiv, 2019
In this note the simple procedure for obtaining the mass spectrum of two-dimensional Toda lattice of $E_8$ type is given.
arxiv  

Mass spectrum and thermodynamics of quasi-conformal gauge theories from gauge/gravity duality [PDF]

open access: yes, 2011
We use gauge/gravity duality to study simultaneously the mass spectrum and the thermodynamics of a generic quasi-conformal gauge theory, specified by its beta function. The beta function of a quasi-conformal theory almost vanishes, and the coupling is almost constant between two widely separated energy scales.
arxiv   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

The spectrum of massive excitations of 3d 3-state Potts model and universality [PDF]

open access: yes, 2006
We consider the mass spectrum of the 3$d$ 3-state Potts model in the broken phase (a) near the second order Ising critical point in the temperature - magnetic field plane and (b) near the weakly first order transition point at zero magnetic field. In the
A. Papa   +27 more
core   +3 more sources

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

T-duality in M-theory and supermembranes [PDF]

open access: yes, 1997
The (q_1,q_2) SL(2,Z) string bound states of type IIB superstring theory admit two inequivalent (T-dual) representations in eleven dimensions in terms of a fundamental 2-brane.
Aharony   +24 more
core   +2 more sources

CRISPR targeting of FOXL2 c.402C>G mutation reduces malignant phenotype in granulosa tumor cells and identifies anti‐tumoral compounds

open access: yesMolecular Oncology, EarlyView.
FOXL2 c.402C>G mutation drives granulosa cell tumors. Using CRISPR technology, we selectively corrected this mutation, reducing malignancy and increasing sensitivity to dasatinib and ketoconazole. Transcriptomic changes revealed potential therapeutic targets, demonstrating CRISPR's promise for treating this rare ovarian cancer.
Sandra Amarilla‐Quintana   +17 more
wiley   +1 more source

Sparticle Mass Spectrum in Grand Unified Theories

open access: yes, 2007
We carry out a detailed analysis of sparticle mass spectrum in supersymmetric grand unified theories. We consider the spectroscopy of the squarks and sleptons in SU(5) and SO(10) grand unified theories, and show how the underlying supersymmetry breaking ...
Altarelli G.   +5 more
core   +1 more source

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