Results 271 to 280 of about 10,829,007 (362)

Internal physiological drivers of leaf development in trees: Understanding the relationship between non‐structural carbohydrates and leaf phenology

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Plant phenology is crucial for understanding plant growth and climate feedback. It affects canopy structure, surface albedo, and carbon and water fluxes. While the influence of environmental factors on phenology is well‐documented, the role of plant intrinsic factors ...
Yunpeng Luo   +8 more
wiley   +1 more source

Role for Complement C5 in Eosinophilic Inflammation of Severe Asthma

open access: yesAllergy, EarlyView.
Complement activation module, particularly C5, is positively associated with eosinophilic inflammation in severe asthma cohorts. Elevated C5 expression correlates with poor lung function improvement and persistent eosinophilic inflammation. Mouse model studies confirm that C5 exacerbates eosinophilic inflammation, highlighting its potential as a ...
Cong Dong   +217 more
wiley   +1 more source

Effect of the Arg16Gly β2‐Adrenergic Receptor Polymorphism on Long‐Term Mepolizumab Response and Clinical Remission in Severe Eosinophilic Asthma: A Genotype‐Stratified, Multicenter Study

open access: yesAllergy, EarlyView.
This study examines the association between the rs1042713 (Arg16Gly) polymorphism of the β2‐adrenergic receptor and the risk of severe eosinophilic asthma, as well as its influence on mepolizumab long‐term effectiveness and clinical remission. The Arg16 allele is associated with increased risk of severe disease and potentially diminished long‐term ...
Santi Nolasco   +38 more
wiley   +1 more source

Interleukin-18 has an Important Role in Differentiation and Maturation of Mucosal Mast Cells.

open access: green, 2018
Nathan L Sandersa   +5 more
openalex   +1 more source

Table S2 from Elevated Mast Cell Abundance Is Associated with Enrichment of CCR2<sup>+</sup> Cytotoxic T Cells and Favorable Prognosis in Lung Adenocarcinoma

open access: gold
Fanfan Fan   +15 more
openalex   +1 more source

Efficacy of House Dust Mite Immunotherapy in Chinese Allergic Rhinitis Patients With Diverse Sensitization Patterns: A Multicenter Study (COVER Study)

open access: yesAllergy, EarlyView.
This prospective multicenter study corroborates the efficacy of AIT with the native HDM allergen extract in Chinese AR patients with diverse HDM sensitization patterns. HDM sensitization pattern affects the efficacy of AIT, with patients sensitized to both major and minor allergens of HDM showing improved outcomes with HDM SCIT.
Qingxiu Xu   +14 more
wiley   +1 more source

Mediation of Polygenic Asthma Risk Through Gene Expression

open access: yesAllergy, EarlyView.
We apply published PRSs in African‐ancestry individuals and quantify the extent to which the PRS‐asthma relationship is mediated by clinical biomarkers and gene‐expression signatures of asthma. We found the best PRS to be the one derived using the largest sample size and including African‐ancestry individuals.
Rakesh Natarajan   +29 more
wiley   +1 more source

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