Results 1 to 10 of about 77,966 (263)

Case Report: Clinicopathological findings of a cutaneous mast cell tumor in a young domestic meerkat (Suricata suricatta) [PDF]

Frontiers in Veterinary Science
A 10-month-old female domestic meerkat (Suricata suricatta) was presented with a cutaneous nodule in the left axillary region. The animal was clinically healthy and radiographs showed no evidence of involvement of visceral organs.
Marco Graziano Castaman, Margherita Orlandi, Martina Baldin, Maria Massaro, Mattia Ridolfi, Maristella Zambelli   +5 more
doaj   +2 more sources

Visceral Mast Cell Tumor and Mastocythemia in a Dog [PDF]

Brazilian Journal of Veterinary Pathology, 2012
Mast cell tumor manifests as a localized proliferation of mast cells in the skin, or less frequently as a systemic disorder, which may be accompanied by the presence of neoplastic mast cells in the peripheral blood (mastocythemia).
Fernanda G. Grano, José Eduardo S. Silva, Guilherme D. Melo, Augusto Schweigert, Paulo C. Ciarlini, Gisele F. Machado   +5 more
doaj   +2 more sources

Expression of mast cell proteases correlates with mast cell maturation and angiogenesis during tumor progression. [PDF]

PLoS ONE, 2012
Tumor cells are surrounded by infiltrating inflammatory cells, such as lymphocytes, neutrophils, macrophages, and mast cells. A body of evidence indicates that mast cells are associated with various types of tumors.
Devandir Antonio de Souza, Vanina Danuza Toso, Maria Rita de Cássia Campos, Vanessa Soares Lara, Constance Oliver, Maria Célia Jamur   +5 more
doaj   +3 more sources

Heterogeneity and prognostic significance of mast cell subsets in the tumor microenvironment of prostate cancer [PDF]

Cancer Immunology, Immunotherapy
Background Prostate cancer (PC) is one of the malignant tumors with high incidence and mortality worldwide in men. Immune cells in the tumor microenvironment (TME), particularly mast cells, play important roles in tumor progression and prognosis. However,
Ruizhe Fang, Shuyang Zhao, Minggui Si, Yinshi Zhang, Ruicong Xu, Jingjia Li   +5 more
doaj   +2 more sources

Increased tumor-associated mast cells facilitate thyroid cancer progression by inhibiting CD8+ T cell function through galectin-9

Brazilian Journal of Medical and Biological Research, 2023
As an important component of solid tumors, mast cells show specific phenotypes in various tumor microenvironments. However, the precise mechanism of mast cell accumulation and the phenotypic features of thyroid cancer (TC) remain largely unknown.
Yanli Hou, Qiang Wang, Li Su, Ying Zhu, Yun Xiao, Fei Feng   +5 more
doaj   +1 more source

Mast cell - tumor cell interaction related gene and microRNA expression profiles in oral squamous cell carcinoma. [PDF]

Front Oncol
Khromov T, Sitte M, Salinas G, Schminke B, Fischer A, Schliephake H, Brockmeyer P.   +6 more
europepmc   +2 more sources

Mast cell modulates tumorigenesis caused by repeated bowel inflammation condition in azoxymethane/dextran sodium sulfate-induced colon cancer mouse model

Biochemistry and Biophysics Reports, 2022
Mast cells infiltrate the inflammatory microenvironment and regulate the production of many pro-inflammatory cytokines and mediators of inflammatory cell production to promote tumor development and growth in intestinal lesions.
Ji-Hyun Lee, Yong-Deok Jeon, Mingjie Xin, Ji-ye Lim, Young-Mi Lee, Dae-Ki Kim   +5 more
doaj   +1 more source

Mast Cells and Skin and Breast Cancers: A Complicated and Microenvironment-Dependent Role

Cells, 2021
Mast cells are important sentinel cells in host defense against infection and major effector cells in allergic disease. The role of these cells in cancer settings has been widely debated.
Mark R. Hanes, Carman A. Giacomantonio, Jean S. Marshall   +2 more
doaj   +1 more source

Amplification of mast cell density in oral squamous cell carcinoma and normal oral mucosa: A comparative study

Journal of Indian Academy of Oral Medicine and Radiology, 2023
Background: Mast cells are thought to be complex, multifaceted cells that are important for tumor angiogenesis and immunopathology. Mast cell buildup at the periphery of the tumor and their production of strong pro- and angiogenic chemicals may be signs ...
Arpita Kabiraj, Vishal, Shantala R Naik, Prashant Gupta, Tanya Khaitan, Jaydeep Samanta   +5 more
doaj   +1 more source

Steering Mast Cells or Their Mediators as a Prospective Novel Therapeutic Approach for the Treatment of Hematological Malignancies

Frontiers in Oncology, 2021
Tumor cells require signaling and close interaction with their microenvironment for their survival and proliferation. In the recent years, Mast cells have earned a greater importance for their presence and role in cancers. It is known that mast cells are
Deeksha Mehtani, Niti Puri
doaj   +1 more source