Results 231 to 240 of about 147,604 (268)
Some of the next articles are maybe not open access.
2007
Mast cells (MCs) are traditionally thought of as a nuisance for its host, for example, by causing many of the symptoms associated with allergic reactions. In addition, recent research has put focus on MCs for displaying harmful effects during various autoimmune disorders.
Gunnar, Pejler +3 more
openaire +2 more sources
Mast cells (MCs) are traditionally thought of as a nuisance for its host, for example, by causing many of the symptoms associated with allergic reactions. In addition, recent research has put focus on MCs for displaying harmful effects during various autoimmune disorders.
Gunnar, Pejler +3 more
openaire +2 more sources
On the Heterogeneity of Mast Cells
Pharmacology, 2008Mast cells from different locations are shown to vary in their histochemical, ultrastructural, cytochemical and functional properties. The clinical consequences of this heterogeneity and possible reasons for its origin are discussed.
openaire +2 more sources
Current Allergy and Asthma Reports, 2016
For half a century, it has been known that the mast cell is the cell responsible for the majority of anaphylactic events. Its mediators, taken as a whole, are capable of producing all of the clinical manifestations of these events. With the discovery of immunoglobulin E (IgE), it was originally felt that the vast majority of anaphylactic episodes were ...
Phil, Lieberman, Lene Heise, Garvey
openaire +2 more sources
For half a century, it has been known that the mast cell is the cell responsible for the majority of anaphylactic events. Its mediators, taken as a whole, are capable of producing all of the clinical manifestations of these events. With the discovery of immunoglobulin E (IgE), it was originally felt that the vast majority of anaphylactic episodes were ...
Phil, Lieberman, Lene Heise, Garvey
openaire +2 more sources
American Journal of Clinical Pathology, 1975
Autopsy of a patient with well-documented myelofibrosis revealed marked proliferation of mast cells associated with areas of bone-marrow and splenic fibrosis. The findings suggest that the local fibrosis represents the healed phase of an inflammatory reaction mediated by mast cells via the release of histamine into the tissue spaces.
W C, Udoji, S A, Razavi
openaire +2 more sources
Autopsy of a patient with well-documented myelofibrosis revealed marked proliferation of mast cells associated with areas of bone-marrow and splenic fibrosis. The findings suggest that the local fibrosis represents the healed phase of an inflammatory reaction mediated by mast cells via the release of histamine into the tissue spaces.
W C, Udoji, S A, Razavi
openaire +2 more sources
Immunological Reviews, 2018
SummaryMast cells are a part of the innate immune system implicated in allergic reactions and the regulation of host‐pathogen interactions. The distribution, morphology and biochemical composition of mast cells has been studied in detail in vitro and on tissue sections both at the light microscopic and ultrastructural level.
Shweta Tikoo +6 more
openaire +2 more sources
SummaryMast cells are a part of the innate immune system implicated in allergic reactions and the regulation of host‐pathogen interactions. The distribution, morphology and biochemical composition of mast cells has been studied in detail in vitro and on tissue sections both at the light microscopic and ultrastructural level.
Shweta Tikoo +6 more
openaire +2 more sources
Science, 1966
Subcutaneous injections of normally well tolerated amounts of hypertonic NaCl or urea solutions produce extensive topical necroses in rats systemically treated with various mast-cell dischargers and mast-cell products. This response is considered to be closely related to mast-cell function, for it cannot be duplicated by systemic treatment with a ...
openaire +2 more sources
Subcutaneous injections of normally well tolerated amounts of hypertonic NaCl or urea solutions produce extensive topical necroses in rats systemically treated with various mast-cell dischargers and mast-cell products. This response is considered to be closely related to mast-cell function, for it cannot be duplicated by systemic treatment with a ...
openaire +2 more sources
Digestive Diseases, 2009
Mast cells (MCs) typically reside at barrier sites of the body, including the intestinal mucosa, and play a vital role in innate host defence. Activated MCs release a wide variety of bioactive mediators. These include preformed mediators stored in the granules (e.g. histamine and tryptase) and newly synthesised mediators (e.g.
openaire +2 more sources
Mast cells (MCs) typically reside at barrier sites of the body, including the intestinal mucosa, and play a vital role in innate host defence. Activated MCs release a wide variety of bioactive mediators. These include preformed mediators stored in the granules (e.g. histamine and tryptase) and newly synthesised mediators (e.g.
openaire +2 more sources
Molecular Immunology, 1982
Mast cells secrete histamine, glycosaminoglycans, arachidonic acid derivatives, enzymes, and possibly whole granules. Physiologic stimuli include the bridging of membrane-bound IgE molecules by antigen, the anaphylatoxins C5a and C3a, and the neurotransmitter acetylcholine.
openaire +2 more sources
Mast cells secrete histamine, glycosaminoglycans, arachidonic acid derivatives, enzymes, and possibly whole granules. Physiologic stimuli include the bridging of membrane-bound IgE molecules by antigen, the anaphylatoxins C5a and C3a, and the neurotransmitter acetylcholine.
openaire +2 more sources
2005
Apoptosis is a physiological form of cell death. Cells undergoing apoptosis execute a genetically controlled program that leads to organized breakdown of cellular structures and ends in phagocytosis of their remains. In mast cells, several mechanisms regulating apoptosis have been identified including growth factors, tumor necrosis factor-alpha ...
Alexander, Gerbaulet +2 more
openaire +2 more sources
Apoptosis is a physiological form of cell death. Cells undergoing apoptosis execute a genetically controlled program that leads to organized breakdown of cellular structures and ends in phagocytosis of their remains. In mast cells, several mechanisms regulating apoptosis have been identified including growth factors, tumor necrosis factor-alpha ...
Alexander, Gerbaulet +2 more
openaire +2 more sources
1963
Publisher Summary This chapter highlights the tissue mast cell. The mast cells are the ubiquitous element of the connective tissue. Carefully made whole mounts of mesentery and skin or spreads of connective tissue afford visualization of the entire mast cell and its environment.
openaire +2 more sources
Publisher Summary This chapter highlights the tissue mast cell. The mast cells are the ubiquitous element of the connective tissue. Carefully made whole mounts of mesentery and skin or spreads of connective tissue afford visualization of the entire mast cell and its environment.
openaire +2 more sources