Choroidal Mast Cells and Their Degranulation Are a Pivotal Trigger for Myopia Development. [PDF]
Shi J +8 more
europepmc +1 more source
Comprehensive analysis and functional validation of key genes in bladder cancer progression
Bladder cancer is highly diverse between patients, making it difficult to accurately predict who will have aggressive disease and poor outcomes. In this study, we integrated single‐cell RNA sequencing with clinical survival data to identify a simple three‐gene signature (FAM3B, C10orf99, and VMP1) that stratifies patients into high‐ and low‐risk groups.
Xiaoning Cheng +9 more
wiley +1 more source
Interactions Between Tryptase-Positive Mast Cells and Melanin-A+ Cells in the Microenvironment of Cutaneous Melanoma. [PDF]
Atiakshin D +16 more
europepmc +1 more source
Biomarkers to predict outcomes in diabetic foot ulcers
Studies attempting to predict the healing outcome of diabetic foot ulcers (DFUs) have investigated various biological materials and recovered molecules that may aid in discriminating wounds that will heal and those that will not heal. This graphical abstract captures the commonly studied classes of biomarkers in the context of DFUs.
Julie Okiro +6 more
wiley +1 more source
Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity. [PDF]
Zhang L +25 more
europepmc +1 more source
Cellular Mechanism and Key Insights in Allergen Immunotherapy for Allergic Rhinitis
ABSTRACT Allergic rhinitis (AR) arises from immune responses mediated by immunoglobulin E (IgE) to inhaled allergens, representing one of the most prevalent chronic conditions worldwide. Although AR may not be a serious ailment, it holds clinical relevance as it underpins numerous complications, serves as a major risk factor for suboptimal asthma ...
Zhe Wang +3 more
wiley +1 more source
Tumor-Infiltrating Mast Cells Enhance Neoadjuvant Therapy Efficacy in ESCC via Modulation of the Desmoplastic Microenvironment. [PDF]
Cui X +8 more
europepmc +1 more source
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng +3 more
wiley +1 more source
Mast Cells in the Solid Tumor Microenvironment: Multiple Roles and Targeted Therapeutic Potential. [PDF]
Lu C +6 more
europepmc +1 more source

