Mastocytosis presenting with mast cell‐mediator release‐associated symptoms elicited by cyclo oxygenase inhibitors: prevalence, clinical, and laboratory features [PDF]
Background Nonsteroidal anti‐inflammatory drugs (NSAIDs) are frequently avoided in mastocytosis, because of a potential increased risk for drug hypersensitivity reactions (DHRs) due to inhibition of cyclo‐oxygenase (COX), subsequent depletion of ...
Tiago Azenha Rama +9 more
doaj +2 more sources
Cognitive, neuropsychiatric and neurological alterations in mastocytosis: A systematic review [PDF]
Background Mastocytosis manifests with multisystemic symptoms, often involving the nervous system. Numerous cognitive, neuropsychiatric and neurological alterations have been reported in multiple observational studies.
Elena Sagües‐Sesé +2 more
doaj +2 more sources
Systemic Mastocytosis: Following the Tyrosine Kinase Inhibition Roadmap [PDF]
Systemic mastocytosis is a rare and heterogeneous disease characterized by mast cell proliferation and activation. KIT is a transmembrane tyrosine kinase which plays a key role in mast cell growth, differentiation and survival. After interaction with its
Miguel Piris-Villaespesa +1 more
doaj +2 more sources
Whole-Exome Sequencing Reveals Recurrent but Heterogeneous Mutational Profiles in Sporadic WHO Grade 1 Meningiomas [PDF]
Human WHO grade 1 meningiomas are generally considered benign tumors; despite this, they account for ≈50% of all recurrent meningiomas. Currently, limited data exist about the mutational profiles of grade 1 meningiomas and patient outcome.
María González-Tablas +28 more
doaj +2 more sources
Insights in Anaphylaxis and Clonal Mast Cell Disorders [PDF]
The prevalence of anaphylaxis among patients with clonal mast cell disorders (MCD) is clearly higher comparing to the general population. Due to a lower frequency of symptoms outside of acute episodes, clonal MCD in the absence of skin lesions might ...
David González-de-Olano +1 more
doaj +2 more sources
Updated Diagnostic Criteria and Classification of Mast Cell Disorders: A Consensus Proposal [PDF]
Mastocytosis is a hematologic neoplasm characterized by expansion and focal accumulation of neoplastic mast cells (MC) in diverse organs, including the skin, bone marrow (BM), spleen, liver, and gastrointestinal tract.
Peter Valent +39 more
doaj +2 more sources
Mastocytosis is one of the eight subcategories of the myeloproliferative neoplasms of the classification of lymphoid and hematopoietic tissues’ tumors of 2008 of World Health Organization; it is an heterogeneous group of myeloproliferative diseases ...
Sandra Nora González-Díaz +3 more
doaj +3 more sources
Pregnancy and Delivery in Patients with Mastocytosis Treated at the Polish Center of the European Competence Network on Mastocytosis (ECNM). [PDF]
OBJECTIVE:To present current guidelines regarding treatment of mastocytosis in pregnancy on the example of observed patients. DESIGN:Case control national study. SETTING:Polish Center of the European Competence Network on Mastocytosis (ECNM).
Katarzyna Ciach +9 more
doaj +2 more sources
Mastocitosis: urticaria pigmentosa
La mastocitosis es una enfermedad rara. Se caracteriza por una proliferación benigna o en raras ocasiones maligna de mastocitos en los tejidos. Puede producir alteraciones tanto sistémicas como cutáneas.
Pedro Antonio Díaz Llanio +4 more
doaj +1 more source
Las mastocitosis están incluidas dentro del grupo de "enfermedades raras" debido a su baja frecuencia. Se caracterizan por el crecimiento y acumulación de causa desconocida de mastocitos en piel y otros órganos. Las manifestaciones clínicas se deben a la
Catalino R Ustáriz-García
doaj +1 more source

