Results 41 to 50 of about 429 (179)

PB2227 COMPASSIONATE USE OF ROPEGINTERFERON TO TREAT MYELOPROLIFERATIVE NEOPLASMS IN TAIWAN

HemaSphere, Volume 3, Issue S1, Page 999, June 2019., 2019
Background: There is a high unmet medical need for therapeutic options for patients suffering from myeloproliferative neoplasms (MPN), who have failed or are not eligible to available treatment options. Ropeginterferon‐alfa‐2b (P1101) is a novel, third generation pegylated interferon‐alfa, recently approved by EMA to treat polycythemia vera (PV ...
C.‐C. Chen, M.‐C. Kuo, Y. ‐.‐J. Su, C.‐E. Huang, C.‐C. Hsu, Y.‐Y. Wu, Y.‐J. Chen, L.‐Y. Shih   +7 more
wiley   +1 more source

PB2229 DISEASE CHARACTERISTICS AND RESPONSE TO TREATMENT OF PATIENTS WITH MYELOFIBROSIS:A MULTICENTRE DESCRIPTIVE, RETROSPECTIVE STUDY FROM SRI LANKA

HemaSphere, Volume 3, Issue S1, Page 999, June 2019., 2019
Background: Myelofibrosis (MF)is a BCR/ABL negative, myeloproliferative neoplasm. The manifestations of MF include constitutional symptoms, splenomegaly, anaemia and other cytopenias. Most of the patients are elderly with multiple comorbidities and cannot undergo, allogeneic stem cell transplantation.
D. Moratuwagama, Y. Costa, S. Senanayake, H. Williams, B. Jayaratne B, V. Rathnamalala, N. Ranasinghe, L. Gooneratne, H. Goonesekara, D. Gunewardena, I. Wijesiriwardene, C. Kulathilake C, A. Jayawardene A, J. D. Silva, I. Dharmasena, N. Perera, N. Mendis, P. Vitharana, R. Jayathunga, H. Gunasekara, L. Basnayake, Y. Samaraweera, T. Sooriyakumar, D. Dissanayake, W. Vidyaratne, K. Jayaratne, H. Alwis, R. Wijeratne, A. Attanayake, S. Athawuda, R. Pullaperuma, B. Somarathna, S. Yoganathan, L. Senerath, V. Gunawardena, B. Balasooriya, D. Epa, B. Fernandopulle, C. Moonesinhge   +38 more
wiley   +1 more source

PB2230 SYSTEMIC MASTOCYTOSIS WITH ASSOCIATED HEMATOLOGIC NEOPLASM, EVOLVING TO SIMULTANEOUS CD33 POSITIVE MAST CELL LEUKEMIA AND ACUTE MYELOID LEUKEMIA, TREATED WITH GEMTUZUMAB‐OZOGAMICIN

HemaSphere, Volume 3, Issue S1, Page 999-1000, June 2019., 2019
Background: Mast cell leukemia (MCL) is an extremely rare subtype of systemic mastocytosis (SM), with only 50 cases described so far. It confers an extremely bad prognosis, with an overall survival of few months. Aims: To describe an extremely rare case of MCL and AML treated with Gemtuzumab‐Ozogamicin (GO).
P. López‐Pereira, Á. Figuera, I. Ormazábal, J. Cornago, E. Sola, M. Quesada, A. Savchuk, V. Lizandro, A. de la Fuente, R. Ayala, I. Álvarez‐Twose, J. L. Steegmann   +11 more
wiley   +1 more source

T‐cell immune profile in blood of systemic mastocytosis: Association with disease features

Allergy, Volume 79, Issue 7, Page 1921-1937, July 2024.
Constitutively activated tumour MC in SM patients are associated with a broad activation of the innate immune response and an altered distribution of other adaptive immune cells. The altered circulating T‐ and NK‐cell immune profile in SM varies depending on disease subtype, the pattern of involvement of haematopoiesis by KITD816V, the HαT genotype and
Alba Pérez‐Pons, Cristina Teodosio, María Jara‐Acevedo, Ana Henriques, Paula Navarro‐Navarro, Andrés C. García‐Montero, Iván Álvarez‐Twose, Quentin Lecrevisse, Rafael Fluxa, Laura Sánchez‐Muñoz, Carolina Caldas, Julio Pozo, Silvia Martín, Teresa Contreras Sanfeliciano, Carlos E. Pedreira, Vitor Botafogo, Oscar González‐López, Andrea Mayado, Alberto Orfao   +18 more
wiley   +1 more source

Nuevas variantes clínicas y moleculares de mastocitosis. Caracterización clínico-biológica e implicaciones terapéuticas [PDF]

, 2017
INTRODUCCIÓN La mastocitosis sistémica (SM) constituye un grupo heterogéneo de enfermedades caracterizadas por la presencia de mastocitos (MCs) patológicos en diferentes órganos y tejidos, entre los que destaca la médula ósea (MO).
Álvarez Twose, Iván
core   +1 more source

Manejo anestésico de paciente con mastocitosis cutánea [PDF]

Revista Chilena de Anestesia, 2021
Álvaro Pérez Fernández-Escandón
doaj   +1 more source

Mastocitosis cutánea difusa en pediatría, una entidad de difícil diagnostico

, 2022
Objective: To present the possibilities of cutaneous mastocytosis in pediatrics. Case presentation: We present the case of a male infant with pemphigoid symptoms who underwent multiple studies suggested by a multidisciplinary team, finally the diagnosis ...
Sanchez Quintero , Karen Lorena, Tarazona Ruiz, Angie Patrícia, Theran León , Juan Sebastián, Ramírez Zambrano , Carlos Julio, Cepeda Bareño , Daniel Andres, Jaimes Hernández , Laura Ximena, Rolanlly Robles, Jhurgen   +6 more
core   +1 more source

Manejo Anestésico en una paciente con Mastocitosis Sistémica

Revista Electrónica de AnestesiaR, 1970
Presentamos el caso de una mujer de 38 años a la que se diagnosticó de Astrocitoma parietal izquierdo subsidiario de tratamiento quirúrgico. Entre sus antecedentes destacaban alergia al diclofenaco, HTA controlada en tratamiento con antagonista del ...
María Mercedes Olvera García
doaj   +1 more source

Mastocitosis cutánea difusa. Reporte de un paciente pediátrico

Revista Alergia México, 2018
Antecedentes: La mastocitosis es un desorden caracterizado por la acumulación patológica de mastocitos en los tejidos, además, se acompaña de síntomas derivados de la activación mastocitaria en la mayoría de los pacientes.
Rodrigo Alonso Gaviria-Rendón, Ricardo Cardona   +1 more
doaj  

Mastocitosis [PDF]

, 2015
La mastocitosis es una de las ocho subcategorías de las neoplasias mieloproliferativas de la clasificación de tumores de tejidos linfoides y hematopoyéticos de 2008 de la Organización Mundial de la Salud; es un grupo heterogéneo de enfermedades ...
Arias Cruz, Alfredo, Palma Gomez, Samuel, González Díaz, Sandra Nora, Pérez Vanzzini, Rafael   +3 more
core   +1 more source