Results 21 to 30 of about 429 (179)

Altered innate immune profile in blood of systemic mastocytosis patients. [PDF]

Clin Transl Allergy, 2022
Abstract Background Mast cells (MC) from systemic mastocytosis (SM) patients release MC mediators that lead to an altered microenvironment with potential consequences on innate immune cells, such as monocytes and dendritic cells (DC). Here we investigated the distribution and functional behaviour of different populations of blood monocytes and DC among
Pérez-Pons A, Jara-Acevedo M, Henriques A, Navarro-Navarro P, García-Montero AC, Álvarez-Twose I, Pedreira CE, Sánchez-Muñoz L, Damasceno D, Caldas C, Muñoz-González JI, Matito A, Flores-Montero J, González-López O, Criado I, Mayado A, Orfao A.   +16 more
europepmc   +2 more sources

Mastocitosis cutánea difusa

Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica, 2003
Se reporta el caso clínico de un paciente con múltiples vesículas y ampollas en la cara y el tronco desde el primer mes de vida, acompañadas de diarrea y vómito asociados con la ingesta de diferentes medicamentos.
María Adelaida Echeverri M, Ana Cristina Ruiz, Claudia Uribe   +2 more
doaj   +1 more source

Markedly Increased Diamine Oxidase During Acute Anaphylaxis Is Associated With an Underlying Clonal Mast Cell Disorder. [PDF]

Clin Exp Allergy
We provide the first evidence that pronounced release of DAO during anaphylaxis is restricted to patients with clonal mast cell disorder. This finding offers possible functional support for the reported association between KIT p.D816V and anaphylaxis severity.
Rijavec M, Kogovšek Ž, Inkret J, Kopač P, Košnik M, Korošec P.   +5 more
europepmc   +2 more sources

Cutaneous Mastocitosis. A singular case

Revista Habanera de Ciencias Médicas, 2015
Introduction: the mastocytosis or mastocytoma are a genodermatosis, of unknown etiologic, for which is included in the frequent strange or few groups of illnesses, it generally appears in the childhood or to the moment to be born, it is related with ...
Jorge Luis Valdés González, Urbano Solis Cartas, Elda María Valdés González   +2 more
doaj   +1 more source

Mastocitosis cutánea. Presentación de un caso Cutaneous mastocytosis: A case presentation

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2010
Las mastocitosis comprenden un grupo de enfermedades que se caracterizan por la acumulación anormal de mastocitos y por la liberación de sus mediadores químicos. Existen formas puramente cutáneas y otras con infiltración de cualquier tejido. Su etiología
Dr. Catalino R. Ustáriz García, Ania Hernández Cabezas   +1 more
doaj   +1 more source

El mastocito y la mastocitosis

Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica, 1991
Se efectúa una revisión de la morfología, bioquímica y funciones del mastocito, célula completa que juega un rol central en las reacciones de hipersensibilidad, pero también en otros cuadros patológicos (urticaria, diátesis atópica, hemangiomas ...
Carlos Escobar R
doaj   +1 more source

Mastocitosis Cutánea: Revisión y actualización [PDF]

Realizar una revisión bibliográfica sobre Mastocitosis cutánea, sintetizando la información de las diferentes formas de manifestación, su clínica, diagnóstico, tratamiento y pronóstico, así como del estado actual de la investigación acerca de nuevos métodos diagnósticos y terapéuticos.
Bosque Blasco, Víctor, Alcaine González, Clara   +1 more
openaire   +2 more sources

A case of high‐risk AML in a patient with advanced systemic mastocytosis

Clinical Case Reports, Volume 11, Issue 7, July 2023., 2023
Abstract Aggressive SM + AML has limited therapeutic options. Even a strong combination of decitabine–venetoclax–midostaurin has a transient effect on AML and a mitigated effect on SM. Larger series are required to identify the best therapeutic strategy.
Manlio Fazio, Calogero Vetro, Uroš Markovic, Andrea Duminuco, Marina Parisi, Cinzia Maugeri, Elisa Mauro, Nunziatina Laura Parrinello, Fabio Stagno, Loredana Villari, Anna Maria Triolo, Stefania Stella, Giuseppe A. Palumbo, Francesco Di Raimondo, Alessandra Romano, Roberta Zanotti   +15 more
wiley   +1 more source

High burden of clonal mast cell disorders and hereditary α-tryptasemia in patients who need Hymenoptera venom immunotherapy. [PDF]

Allergy
In this multicenter study, we have demonstrated that clonal mast cell disease and HαT are more prevalent among individuals who need VIT; one or both was found in 27% of individuals overall. Both diagnoses were highly concentrated among individuals with severe anaphylaxis.
Korošec P, Sturm GJ, Lyons JJ, Marolt TP, Svetina M, Košnik M, Zidarn M, Kačar M, Frelih N, Lalek N, Luzar AD, Zver S, Škerget M, Czarnobilska E, Dyga W, Grle SP, Samarzija M, Arzt-Gradwohl L, Čerpes U, Porebski G, Pevec B, Schadelbauer E, Kopač P, Šelb J, Rijavec M.   +24 more
europepmc   +2 more sources

KITD816V mutation in blood for the diagnostic screening of systemic mastocytosis and mast cell activation syndromes

Allergy, Volume 78, Issue 5, Page 1347-1359, May 2023., 2023
This study evaluates the utility of KITD816V mutational status in blood (vs. bone marrow) for the diagnostic screening of SM and MCAS patients, having a high specificity but a limited sensitivity in patients presenting with clonal MCAS without skin lesions.
Paula Navarro‐Navarro, Iván Álvarez‐Twose, Alba Pérez‐Pons, Ana Henriques, Andrea Mayado, Andrés C. García‐Montero, Laura Sánchez‐Muñoz, Oscar González‐López, Almudena Matito, Carolina Caldas, María Jara‐Acevedo, Alberto Orfao   +11 more
wiley   +1 more source