Results 1 to 10 of about 342 (178)

Cognitive, neuropsychiatric and neurological alterations in mastocytosis: A systematic review [PDF]

Clinical and Translational Allergy, 2023
Background Mastocytosis manifests with multisystemic symptoms, often involving the nervous system. Numerous cognitive, neuropsychiatric and neurological alterations have been reported in multiple observational studies.
Elena Sagües‐Sesé, Natalia García‐Casares, Ivan Álvarez‐Twose   +2 more
doaj   +3 more sources

Mastocytosis presenting with mast cell‐mediator release‐associated symptoms elicited by cyclo oxygenase inhibitors: prevalence, clinical, and laboratory features [PDF]

Clinical and Translational Allergy, 2022
Background Nonsteroidal anti‐inflammatory drugs (NSAIDs) are frequently avoided in mastocytosis, because of a potential increased risk for drug hypersensitivity reactions (DHRs) due to inhibition of cyclo‐oxygenase (COX), subsequent depletion of ...
Tiago Azenha Rama, José Mário Morgado, Ana Henriques, Luis Escribano, Iván Alvarez‐Twose, Laura Sanchez‐Muñoz, André Moreira, José Romão, Alberto Órfão, Almudena Matito   +9 more
doaj   +3 more sources

Mastocitosis cutánea maculopapular infantil: reporte de un caso

Revista Médica Clínica Las Condes, 2019
Resumen: Objetivo: Reportar un caso de mastocitosis cutánea maculopapular de inicio en la infancia y realizar una revisión bibliográfica con énfasis en el diagnóstico, estudio, pronóstico y tratamiento.
Renatta de Grazia, Patricia Apt, Álvaro Ibarra, Ivo Sazunic   +3 more
exaly   +4 more sources

Updated Diagnostic Criteria and Classification of Mast Cell Disorders: A Consensus Proposal [PDF]

HemaSphere, 2021
Mastocytosis is a hematologic neoplasm characterized by expansion and focal accumulation of neoplastic mast cells (MC) in diverse organs, including the skin, bone marrow (BM), spleen, liver, and gastrointestinal tract.
Peter Valent, Cem Akin, Karin Hartmann, Ivan Alvarez-Twose, Knut Brockow, Olivier Hermine, Marek Niedoszytko, Juliana Schwaab, Jonathan J. Lyons, Melody C. Carter, Hanneke Oude Elberink, Joseph H. Butterfield, Tracy I. George, Georg Greiner, Celalettin Ustun, Patrizia Bonadonna, Karl Sotlar, Gunnar Nilsson, Mohamad Jawhar, Frank Siebenhaar, Sigurd Broesby-Olsen, Selim Yavuz, Roberta Zanotti, Magdalena Lange, Boguslaw Nedoszytko, Gregor Hoermann, Mariana Castells, Deepti H. Radia, Javier I. Muñoz-Gonzalez, Wolfgang R. Sperr, Massimo Triggiani, Hanneke C. Kluin-Nelemans, Stephen J. Galli, Lawrence B. Schwartz, Andreas Reiter, Alberto Orfao, Jason Gotlib, Michel Arock, Hans-Peter Horny, Dean D. Metcalfe   +39 more
doaj   +3 more sources

Mastocitosis. Presentación de un caso [PDF]

Revista de Ciencias Médicas de Pinar del Río, 2013
La mastocitosis o mastocitoma es una genodermatosis poco frecuente, de etiología desconocida, incluida en el grupo de "enfermedades raras", que aparece en la infancia generalmente.
Carlos Alberto Blanco Córdova
doaj   +2 more sources

Systemic Mastocytosis: Following the Tyrosine Kinase Inhibition Roadmap [PDF]

Frontiers in Pharmacology, 2020
Systemic mastocytosis is a rare and heterogeneous disease characterized by mast cell proliferation and activation. KIT is a transmembrane tyrosine kinase which plays a key role in mast cell growth, differentiation and survival. After interaction with its
Miguel Piris-Villaespesa, Ivan Alvarez-Twose   +1 more
doaj   +2 more sources

Whole-Exome Sequencing Reveals Recurrent but Heterogeneous Mutational Profiles in Sporadic WHO Grade 1 Meningiomas [PDF]

Frontiers in Oncology, 2021
Human WHO grade 1 meningiomas are generally considered benign tumors; despite this, they account for ≈50% of all recurrent meningiomas. Currently, limited data exist about the mutational profiles of grade 1 meningiomas and patient outcome.
María González-Tablas, María González-Tablas, María González-Tablas, Carlos Prieto, Carlos Prieto, Daniel Arandia, Daniel Arandia, María Jara-Acevedo, María Jara-Acevedo, Álvaro Otero, Álvaro Otero, Daniel Pascual, Daniel Pascual, Laura Ruíz, Laura Ruíz, Iván Álvarez-Twose, Iván Álvarez-Twose, Andrés Celestino García-Montero, Andrés Celestino García-Montero, Andrés Celestino García-Montero, Andrés Celestino García-Montero, Alberto Orfao, Alberto Orfao, Alberto Orfao, Alberto Orfao, María Dolores Tabernero, María Dolores Tabernero, María Dolores Tabernero, María Dolores Tabernero   +28 more
doaj   +2 more sources

Insights in Anaphylaxis and Clonal Mast Cell Disorders [PDF]

Frontiers in Immunology, 2017
The prevalence of anaphylaxis among patients with clonal mast cell disorders (MCD) is clearly higher comparing to the general population. Due to a lower frequency of symptoms outside of acute episodes, clonal MCD in the absence of skin lesions might ...
David González-de-Olano, Iván Álvarez-Twose   +1 more
doaj   +2 more sources

Urticaria pigmentosa de presentación atípica en la infancia: Reporte de un caso clínico

ARS Medica, 2016
La Urticaria Pigmentosa es el tipo más frecuente de mastocitosis cutáneas de inicio en la edad pediátrica, representando el 75% de los casos. Se presenta con máculas y/o pápulas de color amarillo a café-rojizo, usualmente con signo de Darier positivo y ...
Catherina Moll-Manzur, Camila Downey, María Teresa Dossi Cataldo   +2 more
doaj   +2 more sources

Anaphylaxis events in the PIONEER study of avapritinib in indolent systemic mastocytosis [PDF]

World Allergy Organization Journal
Background: Patients with indolent systemic mastocytosis (ISM), a clonal mast cell disease primarily driven by the KIT D816V mutation, often have lifelong debilitating symptoms.
Thanai Pongdee, MD, Mariana Castells, MD, PhD, Cem Akin, MD, Ingunn Dybedal, MD, PhD, Jason Gotlib, MD, Jens Peter Panse, MD, Ivan Alvarez-Twose, MD, PhD, Cristina Morales Cabeza, MD, Sonia Cerquozzi, MD, FRCPC, Peter Vadas, MD, Vidushi Swarup, MS, Pankit Vachhani, MD, Friederike Wortmann, MD, Cecilia Arana Yi, MD, Ilda Bidollari, MD, Kate Newberry, PhD, Daniel Shaheen, PharmD, Karin Hartmann, MD   +17 more
doaj   +2 more sources