Results 41 to 50 of about 474,954 (240)

Modelagem do estímulo-modelo para estabelecer relações condicionais arbitrárias em macacos-prego (Cebus apella)

Arquivos Brasileiros de Psicologia, 2009
Arbitrary conditional discriminations are difficult to obtain in non-human subjects. This study evaluates the efficacy of sample stimulus shaping procedure. Two experiments were carried out.
Ilara Reis Nogueira da Cruz, Katarina Bonfim Kataoka, Ana Cláudia de Oliveira Costa, Marilice Fernandes Garotti, Olavo de Faria Galvão, Romariz da Silva Barros   +5 more
doaj  

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

The Differential Outcomes Effect Using Sensory Outcomes in a Many-to-One Matching-to-Sample Task

Psicologia: Teoria e Pesquisa, 2019
The present study was designed to evaluate the use of sensory outcomes (visual vs. auditory) using a differential outcomes procedure to facilitate learning in a many-to-one matching-to-sample task.
Laura Rebeca Mateos Morfín, Carlos Flores, J. Bruce Overmier   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Ensino de Leitura de Sentenças: Contribuições da Análise do Comportamento

Psicologia: Teoria e Pesquisa
RESUMOO paradigma da equivalência de estímulos tem sido pouco usado para estudar o ensino de leitura de sentenças. Assim, o presente estudo avaliou o efeito de um procedimento de ensino e testes de relações condicionais seguidos pelo encadeamento de ...
Verônica Bender Haydu, Ana Carolina Zuanazzi, Grauben José Alves de Assis, Olvia Misae Kato   +3 more
doaj   +1 more source

Facilitation of equivalence – equivalence responding: generalization of relational responses

International Journal of Psychological Research, 2011
Equivalence-equivalence responding (Eq-Eq) has become a behaviour analytic model of analogical reasoning. In previous works it was demonstrated that the exposition to a non-arbitrary relational task (facilitation procedure) improves performance in Eq-Eq ...
Vicente Perez, Andres Garcia, Jesus Gomez   +2 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Feedback Combinations and Generalized Matching-to-Sample Performance Under Familiar and Unfamiliar Stimuli and Matching Relations

Acta Colombiana de Psicología, 2019
Six groups of high-school students were exposed to a second-order matching-to-sample task and generalization tests trials using familiar and unfamiliar stimuli as well as a new matching relation.
Mario Serrano, Carlos Flores
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

SAMPLE‐SPECIFIC RATIO EFFECTS IN MATCHING TO SAMPLE [PDF]

Journal of the Experimental Analysis of Behavior, 1983
In a symbolic matching‐to‐sample task, pigeons were trained using sample‐specific, fixed‐ratio “observing responses.” Subsequently, in a mixed condition, each sample was presented equally often with each ratio requirement, i.e., the ratios were no longer correlated with the samples.
openaire   +2 more sources