Results 41 to 50 of about 62,132,774 (264)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

FORMACIÓN DE CLASES EQUIVALENTES A TRAVÉS DE REGLAS VERBALES Y FORMATO MANUAL [PDF]

open access: yesActa Colombiana de Psicología, 2008
Equivalent class formation through verbal rules was analyzed. A matching-to-sample procedure for training and probing of conditional discriminations in a “paper and pencil” format was used.
Tovar y Romo, Ángel   +1 more
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Modelagem do estímulo-modelo para estabelecer relações condicionais arbitrárias em macacos-prego (Cebus apella)

open access: yesArquivos Brasileiros de Psicologia, 2009
Arbitrary conditional discriminations are difficult to obtain in non-human subjects. This study evaluates the efficacy of sample stimulus shaping procedure. Two experiments were carried out.
Ilara Reis Nogueira da Cruz   +5 more
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

The Differential Outcomes Effect Using Sensory Outcomes in a Many-to-One Matching-to-Sample Task

open access: yesPsicologia: Teoria e Pesquisa, 2019
The present study was designed to evaluate the use of sensory outcomes (visual vs. auditory) using a differential outcomes procedure to facilitate learning in a many-to-one matching-to-sample task.
Laura Rebeca Mateos Morfín   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Matching Random Samples in Many Dimensions

open access: yesThe Annals of Applied Probability, 1992
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +3 more sources

Basal ganglia and memory retrieval during delayed match-to-sample and non-match-to-sample tasks [PDF]

open access: yesBMC Neuroscience, 2009
Top-down guidance of visual search requires the ability tobias the processing of visual features towards the charac-teristics of the desired object. Whatever form they maytake, these characteristics (that we will call here a templateof the object) have to be transferred from memory to thevisual cortical areas, either from long-term memory orworking ...
Hamker Fred, Vitay Julien
openaire   +2 more sources

Sample-to-sample distances.

open access: yes, 2018
Sample-to-sample distances.
Gottfried Martin (157401)   +4 more
core   +1 more source

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