Results 91 to 100 of about 209,947 (320)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

One-Bit Compressed Sensing by Greedy Algorithms [PDF]

open access: yes, 2013
Sign truncated matching pursuit (STrMP) algorithm is presented in this paper. STrMP is a new greedy algorithm for the recovery of sparse signals from the sign measurement, which combines the principle of consistent reconstruction with orthogonal matching
Gong, Da, Liu, Wenhui, Xu, Zhiqiang
core  

Video compression using matching pursuits [PDF]

open access: yesIEEE Transactions on Circuits and Systems for Video Technology, 1999
The use of matching pursuit (MP) to code video using overcomplete Gabor basis functions has recently been introduced. In this paper, we propose new functionalities such as SNR scalability and arbitrary shape coding for video coding based on matching pursuit.
O.K. Al-Shaykh   +4 more
openaire   +1 more source

Mobile robot visual image hierarchical matching algorithm based on deep reinforcement learning and orthogonal matching pursuit

open access: yesJournal of Applied Science and Engineering
Traditional mobile robot visual image hierarchical matching algorithms can only complete rough matching, which leads to low matching accuracy and long matching time.
Chuanlei Dai, Yuqian Liu, Zhiwei Shi
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Chebushev Greedy Algorithm in convex optimization [PDF]

open access: yes, 2013
Chebyshev Greedy Algorithm is a generalization of the well known Orthogonal Matching Pursuit defined in a Hilbert space to the case of Banach spaces.
Temlyakov, Vladimir
core  

Probabilistic matching pursuit with Gabor dictionaries

open access: yesSignal Processing, 2000
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ferrando, Sebastian Esteban   +3 more
openaire   +3 more sources

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