Results 101 to 110 of about 209,947 (320)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Hybrid Video Coding Based on Bidimensional Matching Pursuit

EURASIP Journal on Advances in Signal Processing, 2004
Hybrid video coding combines together two stages: first, motion estimation and compensation predict each frame from the neighboring frames, then the prediction error is coded, reducing the correlation in the spatial domain.
Lorenzo Granai, Emilio Maggio, Lorenzo Peotta, Pierre Vandergheynst   +3 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A Sharp RIP Condition for Orthogonal Matching Pursuit

Abstract and Applied Analysis, 2013
A restricted isometry property (RIP) condition δK+KθK ...
Wei Dan
doaj   +1 more source

Random Matching Pursuit for Image Watermarking

IEEE Transactions on Circuits and Systems for Video Technology, 2019
The classical solution to an underdetermined system of linear equations mainly has two opposite directions, which lead to either a large $\ell _{2}$ -norm sparse solution or a non-sparse minimum $\ell _{2}$ -norm solution. In this paper, we systematically show that by modifying the well-known basic matching pursuit algorithm originally ...
Guang Hua, Lifan Zhao, Haijian Zhang, Guoan Bi, Yong Xiang   +4 more
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Peak Colocalized Orthogonal Matching Pursuit for Seismic Trace Decomposition

IEEE Access, 2020
Orthogonal matching pursuit (OMP) is an efficient method for decomposing a seismic trace with regard to an atom dictionary. The original OMP optimizes one unique single objective in terms of successively maximizing the inner product between an atom and ...
Yongqing Li, Jun Wang, Hui Li, Peng Ren
doaj   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Bayesian approach with extended support estimation for sparse linear regression

Results in Applied Mathematics, 2019
A greedy algorithm called Bayesian multiple matching pursuit (BMMP) is proposed to estimate a sparse signal vector and its support given m linear measurements. Unlike the maximum a posteriori (MAP) support detection, which was proposed by Lee to estimate
Kyung-Su Kim, Sae-Young Chung
doaj   +1 more source