Results 71 to 80 of about 240,616 (307)

Item format statistics and readability of extended matching questions as an effective tool to assess medical students

open access: yesScientific Reports, 2022
Testing based on multiple choice questions (MCQ) is one of the most established forms of assessment, not only in the medical field. Extended matching questions (EMQ) represent a specific type of MCQ designed to require higher levels of cognition, such as
Anna Frey   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Generating Cohort-specific Earnings through the Secure Query System

open access: yesInternational Journal of Population Data Science
Objectives In collaboration with the U.S. Internal Revenue Service, we are developing a Secure Query System (SQS) to produce earnings and tax statistics for lists of individuals supplied by government agencies or academic institutions.
Amy O'Hara   +2 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Automatic matching of bullet land impressions

open access: yes, 2017
In 2009, the National Academy of Sciences published a report questioning the scientific validity of many forensic methods including firearm examination.
Carriquiry, Alicia   +5 more
core   +1 more source

Heterogeneous Image Matching via a Novel Feature Describing Model

open access: yesApplied Sciences, 2019
Computer vision has been developed greatly in the past several years, and many useful and interesting technologies have been presented and widely applied. Image matching is an important technology based on similarity measurement.
Bin Zhou   +5 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

On the uniqueness of probability matching priors

open access: yes, 2007
Probability matching priors are priors for which Bayesian and frequentist inference, in the form of posterior quantiles, or confidence intervals, agree to some order of approximation.
Staicu, A-M, Reid, N, Reid, Nancy
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Computing Matching Statistics on Repetitive Texts

open access: yes2022 Data Compression Conference (DCC), 2022
Computing the {\em matching statistics} of a string $P[1..m]$ with respect to a text $T[1..n]$ is a fundamental problem which has application to genome sequence comparison. In this paper, we study the problem of computing the matching statistics upon highly repetitive texts.
openaire   +2 more sources

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