Results 81 to 90 of about 240,616 (307)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Brain-Like Navigation Scheme based on MEMS-INS and Place Recognition

open access: yesApplied Sciences, 2019
Animals have certain cognitive competence about the environment so they can correct their navigation errors. Inspired by the excellent navigational behavior of animals, this paper proposes a brain-like navigation scheme to improve the accuracy and ...
Chong Shen   +8 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

A Statistical Duality for Random Matching of Agents

open access: yesMathematical Methods in the Applied Sciences
ABSTRACTWe propose a statistical duality among the preferences and endowments of the agents. Under this duality, the logarithmic prices of random trades among agents in a decentralized economy converge in expectation to the logarithm of the Walrasian equilibrium price in a centralized economy.
Athanasios Yannacopoulos   +4 more
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

Partial identification in the statistical matching problem

open access: yesComputational Statistics & Data Analysis, 2016
The statistical matching problem involves the integration of multiple datasets where some variables are not observed jointly. This missing data pattern leaves most statistical models unidentifiable. Statistical inference is still possible when operating under the framework of partially identified models, where the goal is to bound the parameters rather
Daniel Ahfock   +3 more
openaire   +4 more sources

Matching in thin labour markets: panel data evidence from Finland, 1991-2002 [PDF]

open access: yes
The matching function that postulates a relationship between the flow of new matches and stock of job seekers and vacancies has attracted considerable attention, both theoretical and empirical during the last decade.
Jaakko Pehkonen   +2 more
core  

Gifted and Talented Services for EFL Learners in China: A Step-by-Step Guide to Propensity Score Matching Analysis in R

open access: yesData, 2019
We sought to quantify the effectiveness of a gifted and talented (GT) program, as was provided to university students who demonstrated a talent for learning English as a foreign language (EFL) in China.
Shifang Tang, Fuhui Tong, Xiuhong Lu
doaj   +1 more source

Home - About - Disclaimer - Privacy