Results 81 to 90 of about 510,925 (311)

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu   +8 more
wiley   +1 more source

Analysis of the application of “Jing (精)” in Ben Cao Gang Mu (《本草纲目》 Compendium of Materia Medica)

open access: yes, 2020
Taking the Ben Cao Gang Mu (《本草纲目》 Compendium of Materia Medica) (Jinling edition金陵本) as the research object and “Jing” as the search term, this article summarizes the quantity of medicinals containing “Jing” in Ben Cao Gang Mu, analyzes the connotation ...
Yiwen Yang, Xiaobei Jiang, Baican Yang
semanticscholar   +1 more source

Old School Catalog 1911-12, Chicago College of Medicine and Surgery [PDF]

open access: yes, 1911
https://scholar.valpo.edu/oldschoolcatalogs/1015/thumbnail ...
Valparaiso University
core   +2 more sources

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

open access: yesAdvanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen   +9 more
wiley   +1 more source

Old School Catalog 1924-25, The School of Pharmacy [PDF]

open access: yes, 1924
https://scholar.valpo.edu/oldschoolcatalogs/1001/thumbnail ...
Valparaiso University
core   +1 more source

Smart Nanoparticles Disrupting Energy Supply through Triple Mechanisms to Kill Tumors via Dual Disruption of Mitochondria and Lysosomes

open access: yesAdvanced Science, EarlyView.
This study introduces a biomimetic nanoplatform (MTCA@C) designed for precise cancer therapy. It targets mitochondria to induce dysfunction through photodynamic activation, while concurrently blocking mitophagy via lysosomal alkalinization. The platform further triggers methuosis, resulting in tumor cell death through vacuolization and energy pathway ...
Xiao Xu   +6 more
wiley   +1 more source

New approaches to treating chronic obstructive pulmonary disease with Colla corii asini

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Colla corii asini improves chronic obstructive pulmonary disease (COPD) treatment through anti‐inflammatory, antioxidant, immune‐modulatory, and lung‐nourishing effects, addressing current therapeutic challenges via multitarget mechanisms. Abstract Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death and disability ...
Wenchao Zhang   +5 more
wiley   +1 more source

Old School Catalog 1921-22, The School of Pharmacy [PDF]

open access: yes, 1921
https://scholar.valpo.edu/oldschoolcatalogs/1089/thumbnail ...
Valparaiso University
core   +2 more sources

Macrophage‐targeted cerium‐tannic acid metal‐polyphenol framework nanoenzyme promotes in situ heart valves regeneration through adaptive immunomodulation

open access: yesBMEMat, EarlyView.
A novel nanoenzyme based on cerium ions‐tannic acid metal‐polyphenol framework (FCT) has been developed and loaded onto DHVs for targeting M1 macrophages to reduce their ROS level and reprogram macrophage phenotype, thereby eliminating inflammation, promoting endothelialization and adaptive matrix remodeling of scaffolds, offering a promising strategy ...
Peng Song   +9 more
wiley   +1 more source

The Jefferson Medical College of Philadelphia: From 1825 to 1908 [PDF]

open access: yes, 1908
This brief 1908 history of Jefferson Medical College was written by James W. Holland. An 1868 graduate, Holland went on to become the Dean of Jefferson Medical College in 1887https://jdc.jefferson.edu/jeffersonhistorybooks/1007/thumbnail ...
Holland, James W.
core   +1 more source

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