Results 81 to 90 of about 187,089 (264)

Gigantol ameliorates CCl4-induced liver injury via preventing activation of JNK/cPLA2/12-LOX inflammatory pathway

open access: yesScientific Reports, 2020
Arachidonic acid (AA) signaling pathway is an important constituent of inflammatory processes. In our previous study, it was found that dihydro-stilbene gigantol relieved hepatic inflammation in mice with CCl4-induced acute liver injury. This study aimed
Yaru Xue   +10 more
doaj   +1 more source

A Base‐Mediated Rearrangement of the Benzylic 1,5‐Hexadipyridynyl Moiety

open access: yesChemPlusChem, Accepted Article.
We report a previously unrecognized base‐mediated rearrangement of a benzylic 1,5‐hexadipyridynyl moiety. Upon exposure to base, we show this structural motif to rearrange into a constrained vinyl‐pyridine substituted cyclobutene. Computational modeling indicates that the rearrangement takes place following a route involving stepwise deprotonation ...
Wouter A. Remmerswaal   +8 more
wiley   +1 more source

Museum of Materia Medica(Research Center for Ethnomedicine) [PDF]

open access: yes, 2006
この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されまし
出口 鳴美, 小松 かつ子
core   +1 more source

Medizintheoretische und wissenschaftshistorische Perspektiven einer Revision der Materia medica homoeopathica [PDF]

open access: yes, 2010
In der Homöopathie ist das, was an Patienten und Arzneimittelprüfern beobachtet wird, nicht trivial. Symptome sind hier keine Messwerte, sondern ihre Wahrnehmung, Aufzeichnung und praktische Verwertung sind abhängig von der jeweils zugrunde gelegten ...
Schmidt, Josef M.
core   +1 more source

Hyperbaric Oxygen Regulates Tumor pH to Boost Copper‐Doped Hydroxyethyl Starch Conjugate Nanoparticles Against Cancer Stem Cells

open access: yesExploration, EarlyView.
Hypoxia and acidic microenvironments are characteristic features of solid tumors, driving tumor growth, drug resistance, and metastasis. To address these issues, we combined hyperbaric oxygen therapy with rational designed hydroxyethyl starch‐doxorubicin‐copper nanoparticles to modulate the acidic microenvironment of tumors while enhancing the efficacy
Qingyuan Deng   +9 more
wiley   +1 more source

Immunotropic Properties of Anaferon and Anaferon Pediatric

open access: yesАнтибиотики и Химиотерапия, 2020
Anaferon and pediatric anaferon based on release-active antibodies to interferon-γ (R-A antibodies to INF-γ) proved to be efficient in the treatment of many viral infections.
E. S. Zhavbert   +2 more
doaj  

Saikosaponin b1 Attenuates Liver Fibrosis by Blocking STAT3/Gli1 Interaction and Inducing Gli1 Degradation

open access: yesExploration, EarlyView.
Saikosaponin b1 attenuates liver fibrosis by competitively disrupting the interaction between signal transducer and activator of transcription 3 (STAT3) and glioma‐associated oncogene‐1 (Gli1) in the activated hepatic stellate cells (HSCs). The blocked interaction of STAT3 and Gli1 promotes the degradation of Gli1, inhibits Gli1 transcriptional ...
Meiyu Shao   +15 more
wiley   +1 more source

Pharmacology, toxicity and pharmacokinetics of acetylshikonin: a review

open access: yesPharmaceutical Biology, 2020
Context Acetylshikonin, a naphthoquinone derivative, is mainly extracted from some species of the family Boraginaceae, such as Lithospermum erythrorhizon Sieb. et Zucc., Arnebia euchroma (Royle) Johnst., and Arnebia guttata Bunge. As a bioactive compound,
Zhiqin Zhang   +8 more
doaj   +1 more source

Puerariae lobatae Radix Alleviates Alcoholic Liver Injury by Regulating Circadian Rhythm and Intestinal Flora

open access: yesFood Frontiers, EarlyView.
(A) PLR contains a variety of isoflavones; (B) PLR attenuated alcoholic liver injury; (C) PLR improved intestinal flora dysbiosis; (D) PLR regulated circadian rhythm. ABSTRACT This study used Puerariae lobatae Radix (PLR) to explore its improvement mechanism in mice with alcoholic liver injury from the perspective of intestinal flora and transcriptome.
Yanfang Liao   +7 more
wiley   +1 more source

Squibbs Materia Medica [PDF]

open access: yesAmerican Journal of Ophthalmology, 1919
n ...
openaire   +2 more sources

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