Results 151 to 160 of about 13,024,848 (326)
Coarse grinding parameters on sapphire wafer
Coarse grinding sapphire wafer surface technology is researched by using 61 μm boron carbide, Single factor experiment is used to discuss and test the influence of slurry, lapping pressure and boron carbide content.Resultsshow that the best effect ...
DONG Yunna
doaj
Waikato peat lakes sediment nutrient removal scoping exercise [PDF]
This report was commissioned by Environment Waikato to examine the available methods for internal (bottom sediment) nutrient removal and their suitability for application in the Waikato peat lakes.
Faithfull, Carolyn L. +3 more
core
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
The temperature response of nitrate removal in denitrification beds [PDF]
The addition of reactive nitrogen (Nᵣ) to agricultural systems has helped crop production match human population growth. However, the addition of Nᵣ comes at a cost to environment in the form of ozone destruction, habitat degradation and biodiversity ...
Carter, Anna Marie
core
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Based on the feasibility of the discharge machining of the semiconductor material,it analyze several major factors which influences the material removal rate,including the open circuit voltage,peak current,pulse width and pulse interval.Using central ...
XIN Bin +4 more
doaj
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Material Removal Rate Study on Turning of Al Alloy
Lee Choo Yau, Palanisamy Chockalingam
openaire +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source

