GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Study on the Material Removal Mechanism of FGH99 by Laser-Induced Microjet Assisted Ablation at Different Incidence Angles. [PDF]
Duan Y, Zhang Z, Zhu Z, Ni J.
europepmc +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
A New Surface Decorated Geopolymer Matrix: Insights and Modeling into Comprehensive Sorptive Decolorization Applications. [PDF]
Tunali Akar S, Kara I, Yilmaz A, Akar T.
europepmc +1 more source
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi +8 more
wiley +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Rice Husk-Derived MCM-41 for Efficient Hg(II) Removal: Performance, Mechanism, and Environmental Safety in Real Water Matrices. [PDF]
Bocanegra N +5 more
europepmc +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Study on Water-Jet-Guided Laser-Ultrasonic Grinding Hybrid Processing Technology for SiC<sub>f</sub>/SiC Composite Materials. [PDF]
Yu G, Zhang D, Pei X, Yang F.
europepmc +1 more source
Analysis of distribution of material removal rate in CMP process
Suzuki, Norikazu +2 more
openaire +1 more source

