Results 61 to 70 of about 3,143,235 (349)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Evaluation and improvement of material removal rate with good surface quality in TC4 blisk blade polishing process

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2018
As a kind of efficient and rapid developed surface processing technique, polishing technology is widely used to improve the surface quality in the precision manufacturing of aero-engine blisk blades. Since blisk blade polishing is a metal removal process
Zhen CHEN, Yaoyao SHI, Xiaojun LIN
doaj   +1 more source

Analysis of Tool Utilization from Material Removal Rate Perspective

Procedia CIRP, 2015
An end of life strategy algorithm has been used to study a CNC program to evaluate how the cutting inserts are used in terms of their full utilization. Utilized tool life (UTL) and remaining tool life (RTL) were used to evaluate if the insert has been used to its limits of expected tool life, or contributing to an accumulated tool waste.
Hernández, A.E. Bonilla, Beno, Tomas, Repo, Jari, Wretland, Anders   +3 more
openaire   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Guidelines for etching silicon MEMS structures using fluorine high-density plasmas at cryogenic temperatures [PDF]

, 2002
This paper presents guidelines for the deep reactive ion etching (DRIE) of silicon MEMS structures, employing SF/sub 6//O/sub 2/-based high-density plasmas at cryogenic temperatures.
Boer, Meint J. de, Elwenspoek, Miko, Gardeniers, J.G.E. (Han), Gilde, Melis-Jan, Jansen, Henri V., Roelofs, Gerard, Sasserath, Jay N.   +6 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Calculations of material removal, removal rate, and Preston coefficient in continuous lapping/polishing machines [PDF]

Precision Engineering, 1993
Lapping and polishing machines usually do not have deterministic model to pre-determine removal rate and total material to be removed. The removal process is mainly affected by relative motion between the lap and the substrates, by load applied, and by mechano-chemical characteristics of the substrate material, as well as the abrasive and lap materials.
openaire   +3 more sources

Electrochemical micromachining of galvanized iron sheets: process optimization and performance evaluation

Journal of Electrochemical Science and Engineering
Electrochemical micromachining (ECMM) is a promising non-traditional technique for fabricating micro-features on conductive materials with high precision and minimal thermal effects.
Nadanasabapathi Sivashankar, Kadhiresan Santhanam, Shikandar Prasad, Mamidala Jawahar, Rajasekaran Thanigaivelan   +4 more
doaj   +1 more source

Magnetic relaxation and magnetization field dependence measurements in La0.5Ca0.5MnO3

, 2000
We reported a systematic change in the average magnetic relaxation rate, after the application and removal of a 5 T magnetic field, in a polycrystalline sample of La0.5Ca0.5MnO3. Magnetic relaxation measurements and magnetization versus field curves were
F.M Araujo-Moreira, Huang, J López, Labarta, Moritomo, Mydosh, P.N Lisboa-Filho, Roy, W.A Ortiz, W.A.C Passos, Xiao   +10 more
core   +3 more sources

Reactive Atom Plasma (RAP) figuring machine for meter class optical surfaces [PDF]

, 2013
A new surface figuring machine called Helios 1200 is presented in this paper. It is designed for the figuring of meter sized optical surfaces with form accuracy correction capability better than 20 nm rms within a reduced number of iterations.
Castelli, Marco, Jourdain, Renaud, Proscia, David, Shore, Paul, Sommer, P.   +4 more
core   +1 more source