Results 131 to 140 of about 1,702,166 (311)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

In Situ Monitoring of Microwave Processing of Materials at High Temperatures through Dielectric Properties Measurement. [PDF]

open access: yesMaterials (Basel), 2016
Garcia-Baños B   +4 more
europepmc   +1 more source

Containerless high temperature property measurements by atomic fluorescence [PDF]

open access: yes
Containerless high temperature processing and material property measurements are discussed. Researchers developed methods for non-contact suspension, heating, and property measurement for materials at temperatures up to 3,680K, the melting point of ...
Nordine, Paul C., Shiffman, Robert A.
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Tensile behavior of Fe-40Al alloys with B and Zr additions [PDF]

open access: yes
Both Fe-40Al and Fe-40Al-0.1Zr with and without B were produced by the hot extrusion of powdered metal. Tensile properties were determined from room temperature to 1100 K in air.
Gaydosh, D. J., Nathal, M. V.
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Properties of Materials at High Temperatures Steel

open access: yes, 1983
The objectives of the technical committee are to identify those properties and characteristics, which are of importance, survey the existing knowledge, evaluate the data and the relevant literature, suggest activity in areas not already covered and provide facilities for the dissemination of information in papers and by discussion.
openaire   +1 more source

Very high temperature chemistry: Science justification for containerless experimentation in space [PDF]

open access: yes
A summary is presented of the justification for application of containerless processing in space to high temperature science. Low earth orbit offers a gravitational environment that allows samples to be positioned in an experimental apparatus by very ...
Hofmeister, William H., Nordine, Paul
core   +1 more source

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