Results 51 to 60 of about 1,702,166 (311)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Improvement of Strength and Impact Toughness for Cold-Worked Austenitic Stainless Steels Using a Surface-Cracking Technique

open access: yesMetals, 2018
For cryogenic applications, materials must be cautiously selected because of a drastic degradation in the mechanical properties of materials when they are exposed to very low temperatures.
Kwangyoon Kim   +9 more
doaj   +1 more source

Nanocrystalline cathodes for PC-SOFCs based on BCZY [PDF]

open access: yes, 2016
Perovskites based on BaCeO3-δ exhibit the highest proton conductivity among this class of materials, however, they are susceptible to hydration and carbonation in presence of water vapor and CO2 [1].
Dos Santos-Gómez, Lucía   +4 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Nanocrystalline cathodes for PC-SOFCs [PDF]

open access: yes, 2015
Ceramic proton conductors are of great interest for the development of solid oxide fuel cells (PC-SOFC) operating at relatively low temperatures between 400 and 700 ºC.
Dos Santos-Gómez, Lucía
core  

First-principles, atomistic thermodynamics for oxidation catalysis

open access: yes, 2002
Present knowledge of the function of materials is largely based on studies (experimental and theoretical) that are performed at low temperatures and ultra-low pressures. However, the majority of everyday applications, like e.g.
C. H. F. Peden   +6 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Tungsten material properties at high temperature and high stress

open access: yes, 2010
This paper has been withdrawn by the author - it has been published ...
Skoro, G. P.   +5 more
openaire   +2 more sources

Temperature dependent refractive index of silicon and germanium [PDF]

open access: yes, 2006
Silicon and germanium are perhaps the two most well-understood semiconductor materials in the context of solid state device technologies and more recently micromachining and nanotechnology.
Frey, Bradley J.   +2 more
core   +3 more sources

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