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Advanced maternal age

Obstetrics, Gynaecology & Reproductive Medicine, 2011
Delayed childbearing is a growing trend in developed countries. Between 1989 and 2009, the number of live births to UK women over 40 almost trebled. This accelerating demographic shift is of major clinical and public health concern, because advanced maternal age has consistently been associated with adverse pregnancy outcomes. Current evidence suggests
Mills, Tracey A., Lavender, Tina
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Decreased maternal age with hydranencephaly

American Journal of Medical Genetics, 1997
We studied parental ages of institutionalized children with hydranencephaly. Mothers under age 20 years and under age 18 years were, respectively, 5 and 10 times as frequent as in the general population, and 3 and 4 times more frequent than for institutionalized control patients.
M S, Lubinsky, W, Adkins, E G, Kaveggia
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Alzheimer's Disease and Maternal Age

Journal of the American Geriatrics Society, 1982
Findings from several studies suggest a relationship between Alzheimer's disease and0020Down's syndrome. It has long been known that advanced maternal age is a risk factor for Down's syndrome, and that mothers who give birth to a child with this syndrome have characteristics consistent with accelerated aging.
D, Cohen, C, Eisdorfer, J, Leverenz
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Maternal Age and Children's Ability

Perceptual and Motor Skills, 1978
Associations of maternal age at birth and subsequent intelligence test scores of children were examined in a series of over 1500 young men from the Netherlands. All subjects were members of 2-child families and were resident in Amsterdam at age 19 yr.
P, Zybert, Z, Stein, L, Belmont
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Maternal Age and Parental Loss

British Journal of Psychiatry, 1968
Maternal age at parturition, birth order, and parental loss have all been extensively investigated as possible causal or concomitant factors in a wide variety of mental disorders. Thus, to take an extreme example, the influence of maternal age on one of the two main kinds of mongolism is well known and can hardly have other than a biological ...
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Maternal Age and Autistic Children

Journal of Developmental & Behavioral Pediatrics, 1984
Maternal age was examined in 52 autistic children. Two matched control groups were also investigated. Both were matched with the autistic group on age, sex, and birth order. In addition, the first control group was matched with the autistic group according to IQ, while the second control group was composed of normally intelligent children and matched ...
Steinhausen, H. C.   +3 more
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Down's Syndrome and Maternal Age

Nature, 1969
THE risk of producing offspring with mongolism (Down's syndrome) increases abruptly with maternal age after the age of 30. German1 argued that a decreasing frequency of coitus with age, and an increase in the average interval between the follicular release and the fertilization of the female germ cell, might account for the observed age dependence.
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Very advanced maternal age

The Obstetrician & Gynaecologist, 2020
Key content Increasing fertility options have led to increased birth rates among women over the age of 45 years. Most women aged 45 years or older conceive via assisted reproductive technologies, which are associated with increased risks to both mother and fetus.
Alice Howell, Margaret Blott
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Maternal Residential Atrazine Exposure and Gastroschisis by Maternal Age

Maternal and Child Health Journal, 2012
Previous literature has suggested a link between maternal exposure to atrazine (the most commonly used herbicide in the US) and risk for gastroschisis (a birth defect that involves incomplete closure of the abdominal wall). Our objective was to evaluate the relationship between maternal atrazine exposure and gastroschisis risk by maternal age.
A J, Agopian   +4 more
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Maternal age and infantile autism

Journal of Autism and Developmental Disorders, 1980
In a total population survey of childhood psychosis in the region of Göteborg, 20 children (2 in every 10,000) fulfilled the diagnostic criteria for infantile autism formulated by Rutter. There was a male preponderance with 15 boys and 5 girls. Eighty-five percent of the mothers were older than average. Mean maternal age in the autistic sample was 30.7
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