Results 51 to 60 of about 1,081,271 (339)

Cumulative Live-Birth Rates by Maternal Age after One or Multiple In Vitro Fertilization Cycles: An Institutional Experience [PDF]

International Journal of Fertility and Sterility, 2020
Background The aim of this retrospective study is to investigate the cumulative live birth rate (CLBR) following one or more completed in vitro fertilization (IVF) cycles (up to 6 cycles) stratified by maternal age and type of infertility. Materials
Dalia Khalife, Anwar Nassar, Ali Khalil, Johnny Awwad, Antoine Abu Musa, Antoine Hannoun, Lina El Taha, Fatin Khalifeh, May Abiad, Ghina Ghazeeri   +9 more
doaj   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

Perfluorooctane Sulfonate (PFOS) and Related Perfluorinated Compounds in Human Maternal and Cord Blood Samples: Assessment of PFOS Exposure in a Susceptible Population during Pregnancy [PDF]

, 2004
Fluorinated organic compounds (FOCs), such as perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorooctane sulfonylamide (PFOSA), are widely used in the manufacture of plastic, electronics, textile, and construction material in the ...
Akiko Uno, Calafat AM, Fumihiro Sata, Fumio Okada, Hiroyuki Nakazawa, Koichi Inoue, Reiko Kishi, Rie Ito, Seiko Sasaki, Shizue Kato, Sonomi Nakajima, U.S. EPA, Yasuaki Saijo, Yoshihiro Yoshimura   +13 more
core   +2 more sources

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Mitochondrial function of human embryo: Decline in their quality with maternal aging

Reproductive Medicine and Biology, 2022
Background Female fertility declines with age, due to increased chromosomal aneuploidy and possible reduced mitochondrial function in the embryo.
Shu Hashimoto, Yoshiharu Morimoto
doaj   +1 more source

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Bilinen ve Olası Risk Faktörlerinin Birlikteliğinin Gestasyonel Diyabetes Mellitus Gelişimine Etkisi

Ankara Medical Journal, 2018
Objectives: Advanced maternal age, obesity, presence of family history of diabetes and macrosomic infant delivery are common risk factors for gestational diabetes (GDM).
Eren Gürkan, Emre Dirican, Neşe Bülbül   +2 more
doaj   +1 more source

Protective Effect of Maternal First-Trimester Low Body Mass Index Against Macrosomia: A 10-Year Cross-Sectional Study

Frontiers in Endocrinology, 2022
ObjectiveWe aimed to assess whether maternal first-trimester low body mass index (BMI) has a protective effect against macrosomia.MethodsThis was a cross-sectional study from January 1, 2011, to June 30, 2021, and 84,900 participants were included.
Yongqing Sun, Yongqing Sun, Man Zhang, Man Zhang, Ruixia Liu, Ruixia Liu, Jingjing Wang, Jingjing Wang, Kai Yang, Kai Yang, Qingqing Wu, Qingqing Wu, Wentao Yue, Wentao Yue, Chenghong Yin, Chenghong Yin   +15 more
doaj   +1 more source

The impact of HIV exposure and maternal Mycobacterium tuberculosis infection on infant immune responses to bacille Calmette-Guérin vaccination. [PDF]

, 2015
OBJECTIVE: The objective of this study is to assess the effect of maternal HIV and Mycobacterium tuberculosis (Mtb) infection on cellular responses to bacille Calmette-Guérin (BCG) immunization. DESIGN: A mother-infant cohort study.
Adegnika, Borges-Almeida, Brahmbhatt, Chougnet, Clerici, Combadiere, Cotton, Dauby, Economides, Elliott, Elrefaei, Embree, Epalza, Hanekom, Jones, Kampmann, Kemp, Koyanagi, Kuhn, Madhi, Malhotra, Malhotra, Mansoor, Marinda, Mazzola, McNally, Miles, Nakiyingi, Newell, Nielsen, Ono, Otieno, Puissant-Lubrano, Rahman, Resino, Rich, Roederer, Scholzen, Schramm, Schramm, Shapiro, Soares, Torre, Van Rie, Velilla, Weir   +45 more
core   +2 more sources

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source